Rabbit polyclonal MYH7 antibody (A7564)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MYH7 antibody (A7564)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal MYH7 antibody.

Alternative names:

Check alternative names for the antibody

Expand

CMH1 antibody, MPD1 antibody, SPMD antibody, SPMM antibody, CMD1S antibody, MYHCB antibody
Beta myosin heavy chain antibody|cardiac muscle beta isoform antibody|CMD1S antibody|CMH1 antibody|MPD1 antibody|MYH7 antibody|MYH7_HUMAN antibody|Myhc slow antibody|MyHC-beta antibody|MyHC-slow antibody|MYHCB antibody|Myopathy, distal 1 antibody|Myosin heavy chain (AA 1-96) antibody|Myosin heavy chain 7 antibody|Myosin heavy chain antibody|Myosin heavy chain slow isoform antibody|Myosin heavy chain, cardiac muscle beta isoform antibody|Myosin, heavy chain 7, cardiac muscle, beta antibody|Myosin, heavy polypeptide 7, cardiac muscle, beta antibody|Myosin-7 antibody|Rhabdomyosarcoma antigen MU RMS 40.7A antibody|SPMD antibody|SPMM antibody|Anti-Slow Skeletal Myosin Heavy chain antibody [NOQ7.5.4D] (ab11083)

SCBT cat No: sc-71575|sc-53089|sc-53090|sc-168678|

Name

Rabbit polyclonal MYH7 antibody

Catalogue No.

A7564

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human MYH7

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 223kDa/Observed: Refer to figures

Formulation

MYH7 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MYH7 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CMH1 antibody, MPD1 antibody, SPMD antibody, SPMM antibody, CMD1S antibody, MYHCB antibody

Database links

Human UniProt/Swiss-Prot:P12883

Protein names

CMH1, MPD1, SPMD, SPMM, CMD1S, MYHCB

Protein function

Muscle contraction.

Protein tissue specificity

Both wild type and variant Gln-403 are detected in skeletal muscle (at protein level).

Protein sequence and domain

The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.; Limited proteolysis of myosin heavy chain produces 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). HMM can be further cleaved into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.; Contains 1 IQ domain.; Contains 1 myosin motor domain.

Protein cellular localization

Cytoplasm, myofibril. Note: Thick filaments of the myofibrils.

Background

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.

Research area

All research areas>Structural Proteins>Myosin
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus can customize MYH7 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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