Rabbit polyclonal MYOT antibody (A6439)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal MYOT antibody (A6439)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

MFM3 antibody, TTID antibody, TTOD antibody, LGMD1 antibody, LGMD1A antibody
57 kDa cytoskeletal protein antibody|LGMD 1 antibody|LGMD1 antibody|Myofibrillar titin like Ig domains protein antibody|Myofibrillar titin-like Ig domains protein antibody|Myot antibody|MYOTI_HUMAN antibody|Myotilin antibody|Titin immunoglobulin domain protein antibody|TTID antibody|TTID protein antibody|Anti-Myotilin antibody (ab68915)

SCBT cat No: sc-393958|sc-15237|sc-393957|

Name

Rabbit polyclonal MYOT antibody

Catalogue No.

A6439

Reactivity

Human

Immunogen

Recombinant protein of human MYOT

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 55kDa/Observed: Refer to Figures

Formulation

MYOT antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

MYOT antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MFM3 antibody, TTID antibody, TTOD antibody, LGMD1 antibody, LGMD1A antibody

Database links

Human UniProt/Swiss-Prot:Q9UBF9

Protein names

MFM3, TTID, TTOD, LGMD1, LGMD1A

Protein function

Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells.

Protein tissue specificity

Expressed in skeletal muscle (at protein level). Expressed in skeletal muscle, heart, bone marrow and thyroid gland.

Protein sequence and domain

Belongs to the myotilin/palladin family.; Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

Protein cellular localization

Cell membrane, sarcolemma . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . Note: Sarcomeric, also localized to the sarcolemma . Colocalizes with MYOZ1 at the Z-lines in skeletal muscle .

Background

This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Note

AntibodyPlus can customize MYOT antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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