Rabbit polyclonal NCK2 antibody (A7750)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal NCK2 antibody (A7750)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal NCK2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

GRB4 antibody, NCKbeta antibody
Cytoplasmic protein NCK2 antibody|GRB4 antibody|Growth factor receptor bound protein 4 antibody|NCK adaptor protein 2 antibody|Nck-2 antibody|NCK2 antibody|NCK2_HUMAN antibody|NCKbeta antibody|Non-catalytic region of tyrosine kinase adaptor protein 2 antibody|Noncatalytic region of tyrosine kinase beta antibody|SH2/SH3 adaptor protein NCK-beta antibody|Anti-Nck beta antibody [EPR3333] (ab109239)

SCBT cat No:

Name

Rabbit polyclonal NCK2 antibody

Catalogue No.

A7750

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human NCK2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 43kDa/Observed: Refer to figures

Formulation

NCK2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

NCK2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

GRB4 antibody, NCKbeta antibody

Database links

Human UniProt/Swiss-Prot:O43639

Protein names

GRB4, NCKbeta

Protein function

Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.

Protein tissue specificity

Ubiquitous.

Protein sequence and domain

Contains 1 SH2 domain.; Contains 3 SH3 domains.

Protein post-translational modifications

Phosphorylated.

Protein cellular localization

Cytoplasm . Endoplasmic reticulum .

Background

This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Note

AntibodyPlus can customize NCK2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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