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Rabbit polyclonal NCL antibody (A5904)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal NCL antibody.
Check alternative names for the antibodyExpand
C23 antibody|FLJ45706 antibody|MS1116 antibody|NCL antibody|Nucl antibody|NUCL_HUMAN antibody|Nucleolin antibody|Protein C23 antibody|Anti-Nucleolin antibody (ab22758)
SCBT cat No: sc-515312|sc-17826|sc-9893|sc-13057|sc-55486|sc-34400|sc-8031|
Rabbit polyclonal NCL antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human NCL
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 76kDa/Observed: Refer to Figures
NCL antibody was tube-contained.
NCL antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5′-UUAGGG-3′ repeats more tightly than the telomeric single-stranded DNA 5′-TTAGGG-3′ repeats.
|Protein sequence and domain|| |
Contains 4 RRM (RNA recognition motif) domains.
|Protein post-translational modifications|| |
Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group (By similarity).
|Protein cellular localization|| |
Nucleus, nucleolus. Cytoplasm. Note: Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
AntibodyPlus can customize NCL antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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