Rabbit polyclonal NCL antibody (A5904)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal NCL antibody (A5904)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal NCL antibody.

Alternative names:

Check alternative names for the antibody

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C23 antibody
C23 antibody|FLJ45706 antibody|MS1116 antibody|NCL antibody|Nucl antibody|NUCL_HUMAN antibody|Nucleolin antibody|Protein C23 antibody|Anti-Nucleolin antibody (ab22758)

SCBT cat No: sc-515312|sc-17826|sc-9893|sc-13057|sc-55486|sc-34400|sc-8031|

Name

Rabbit polyclonal NCL antibody

Catalogue No.

A5904

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human NCL

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 76kDa/Observed: Refer to Figures

Formulation

NCL antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

NCL antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

C23 antibody

Database links

Human UniProt/Swiss-Prot:P19338

Protein names

C23

Protein function

Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5′-UUAGGG-3′ repeats more tightly than the telomeric single-stranded DNA 5′-TTAGGG-3′ repeats.

Protein sequence and domain

Contains 4 RRM (RNA recognition motif) domains.

Protein post-translational modifications

Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group (By similarity).

Protein cellular localization

Nucleus, nucleolus. Cytoplasm. Note: Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Background

Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.

Note

AntibodyPlus can customize NCL antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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