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Rabbit polyclonal NCS1 antibody (A6455)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal NCS1 antibody.
Check alternative names for the antibodyExpand
FLUP antibody, FREQ antibody
9430075O15Rik antibody|A730032G13Rik antibody|AI836659 antibody|DKFZp761L1223 antibody|FLUP antibody|FREQ antibody|Frequenin antibody|Frequenin homolog (Drosophila) antibody|Frequenin homolog antibody|Frequenin like protein antibody|Frequenin, Drosophila, homolog of antibody|Frequenin-like protein antibody|Frequenin-like ubiquitous protein antibody|Mfreq antibody|NCS 1 antibody|NCS-1 antibody|ncs1 antibody|NCS1_HUMAN antibody|Neuronal calcium sensor 1 antibody|Neuronal Calicum Sensor 1 antibody|Anti-NCS1 antibody [EPR7699] (ab129166)
SCBT cat No: sc-136000|sc-13037|sc-376206|sc-13166|
Rabbit polyclonal NCS1 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human NCS1
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 22kDa/Observed: Refer to Figures
NCS1 antibody was tube-contained.
NCS1 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
FLUP antibody, FREQ antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity).
|Protein sequence and domain|| |
Belongs to the recoverin family.; Contains 4 EF-hand domains.
|Protein cellular localization|| |
Golgi apparatus . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Cytoplasm, perinuclear region . Cytoplasm . Cell membrane ; Peripheral membrane protein. Membrane ; Lipid-anchor . Note: Associated with Golgi stacks. Post-synaptic densities of dendrites, and in the pre-synaptic nerve terminal at neuromuscular junctions.
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
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|Product type|| |
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