Rabbit polyclonal NCS1 antibody (A6455)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal NCS1 antibody (A6455)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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FLUP antibody, FREQ antibody
9430075O15Rik antibody|A730032G13Rik antibody|AI836659 antibody|DKFZp761L1223 antibody|FLUP antibody|FREQ antibody|Frequenin antibody|Frequenin homolog (Drosophila) antibody|Frequenin homolog antibody|Frequenin like protein antibody|Frequenin, Drosophila, homolog of antibody|Frequenin-like protein antibody|Frequenin-like ubiquitous protein antibody|Mfreq antibody|NCS 1 antibody|NCS-1 antibody|ncs1 antibody|NCS1_HUMAN antibody|Neuronal calcium sensor 1 antibody|Neuronal Calicum Sensor 1 antibody|Anti-NCS1 antibody [EPR7699] (ab129166)

SCBT cat No: sc-136000|sc-13037|sc-376206|sc-13166|

Name

Rabbit polyclonal NCS1 antibody

Catalogue No.

A6455

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human NCS1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 22kDa/Observed: Refer to Figures

Formulation

NCS1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

NCS1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

FLUP antibody, FREQ antibody

Database links

Human UniProt/Swiss-Prot:P62166

Protein names

FLUP, FREQ

Protein function

Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity).

Protein sequence and domain

Belongs to the recoverin family.; Contains 4 EF-hand domains.

Protein cellular localization

Golgi apparatus . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Cytoplasm, perinuclear region . Cytoplasm . Cell membrane ; Peripheral membrane protein. Membrane ; Lipid-anchor . Note: Associated with Golgi stacks. Post-synaptic densities of dendrites, and in the pre-synaptic nerve terminal at neuromuscular junctions.

Background

This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize NCS1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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