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Rabbit polyclonal NDRG2 antibody (A5319)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal NDRG2 antibody (A5319)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
Recommended dilution:
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Image descriptions:
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Alternative names:
Check alternative names for the antibody
ExpandSYLD antibody
NDRG 2 antibody|NDRG2 antibody|NDRG2_HUMAN antibody|Protein NDRG2 antibody|Protein Syld709613 antibody|SYLD antibody|Syld709613 protein antibody|Anti-NDRG2 antibody [EPR11910] (ab174850)
SCBT cat No: sc-376202|sc-365223|sc-19468|sc-365080|sc-50345|sc-19467|
| Name | Rabbit polyclonal NDRG2 antibody |
|---|---|
| Catalogue No. | A5319 |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant protein of human NDRG2 |
| Host | Rabbit |
| Applications | WB, IHC |
| Recommended dilution | WB 1:500 – 1:2000 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Molecular weight | Predicted: 41kDa/Observed: Refer to Figures |
| Formulation | NDRG2 antibody was tube-contained. |
| Purification | NDRG2 antibody was purified using affinity purification. |
| Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
| Alternative antibody names | SYLD antibody |
| Database links | Human UniProt/Swiss-Prot:Q9UN36 |
| Protein names | SYLD |
| Protein function | Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation. |
| Protein tissue specificity | Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level). |
| Protein sequence and domain | Belongs to the NDRG family. |
| Protein cellular localization | Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone . Note: In neurons, seems to concentrate at axonal growth cone. Perinuclear in neurons (By similarity). |
| Background | This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. |
| Research area | All research areas>Signaling Intermediates>NDRG |
| Note | AntibodyPlus can customize NDRG2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
| Product type | Primary antibody |
| Supplier | ABclonal Inc. |
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