Rabbit polyclonal NDRG2 antibody (A5319)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal NDRG2 antibody (A5319)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal NDRG2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

SYLD antibody
NDRG 2 antibody|NDRG2 antibody|NDRG2_HUMAN antibody|Protein NDRG2 antibody|Protein Syld709613 antibody|SYLD antibody|Syld709613 protein antibody|Anti-NDRG2 antibody [EPR11910] (ab174850)

SCBT cat No: sc-376202|sc-365223|sc-19468|sc-365080|sc-50345|sc-19467|

Name

Rabbit polyclonal NDRG2 antibody

Catalogue No.

A5319

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human NDRG2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 41kDa/Observed: Refer to Figures

Formulation

NDRG2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

NDRG2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SYLD antibody

Database links

Human UniProt/Swiss-Prot:Q9UN36

Protein names

SYLD

Protein function

Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.

Protein tissue specificity

Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).

Protein sequence and domain

Belongs to the NDRG family.

Protein cellular localization

Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone . Note: In neurons, seems to concentrate at axonal growth cone. Perinuclear in neurons (By similarity).

Background

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Research area

All research areas>Signaling Intermediates>NDRG
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize NDRG2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!