Rabbit polyclonal NFASC antibody (A3053)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal NFASC antibody (A3053)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

NF antibody, NRCAML antibody
KIAA0756 antibody|Neurofascin antibody|Neurofascin homolog antibody|NF antibody|Nfasc antibody|NFASC_HUMAN antibody|NRCAML antibody|Anti-Neurofascin antibody (ab31457)

SCBT cat No: sc-67206|sc-51153|

Name

Rabbit polyclonal NFASC antibody

Catalogue No.

A3053

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human NFASC

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 150kDa/Observed: Refer to Figures

Formulation

NFASC antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

NFASC antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NF antibody, NRCAML antibody

Database links

Human UniProt/Swiss-Prot:O94856

Protein names

NF, NRCAML

Protein function

Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions.

Protein sequence and domain

Homophilic adhesion is primarily mediated by the interaction of the second Ig-like domains.Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.; Contains 5 fibronectin type-III domains.; Contains 6 Ig-like C2-type (immunoglobulin-like) domains.

Protein cellular localization

Cell membrane; Single-pass type I membrane protein.

Background

This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.

Note

AntibodyPlus can customize NFASC antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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