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Rabbit polyclonal NFASC antibody (A3053)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal NFASC antibody.
Check alternative names for the antibodyExpand
NF antibody, NRCAML antibody
KIAA0756 antibody|Neurofascin antibody|Neurofascin homolog antibody|NF antibody|Nfasc antibody|NFASC_HUMAN antibody|NRCAML antibody|Anti-Neurofascin antibody (ab31457)
SCBT cat No: sc-67206|sc-51153|
Rabbit polyclonal NFASC antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human NFASC
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 150kDa/Observed: Refer to Figures
NFASC antibody was tube-contained.
NFASC antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
NF antibody, NRCAML antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Cell adhesion, ankyrin-binding protein which may be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions.
|Protein sequence and domain|| |
Homophilic adhesion is primarily mediated by the interaction of the second Ig-like domains.Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.; Contains 5 fibronectin type-III domains.; Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
|Protein cellular localization|| |
Cell membrane; Single-pass type I membrane protein.
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.
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|Product type|| |
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