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Rabbit polyclonal NFATC3 antibody (A6666)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal NFATC3 antibody.
Check alternative names for the antibodyExpand
NFAT4 antibody, NFATX antibody
C80703 antibody|cytoplasmic 3 antibody|D8Ertd281e antibody|NF AT4 antibody|NF ATc3 antibody|NF-AT4 antibody|NF-ATc3 antibody|NFAC3_HUMAN antibody|NFATc3 antibody|NFATx antibody|Nuclear factor of activated T cells, cytoplasmic 3 antibody|nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 antibody|Nuclear factor of activated T-cells antibody|T cell transcription factor NFAT4 antibody|T-cell transcription factor NFAT4 antibody|Anti-NFAT4 antibody (ab93628)
SCBT cat No: sc-23814|sc-1152|sc-8405|sc-8321|sc-271127|sc-271597|sc-1153|sc-271091|sc-13036|sc-32989|sc-32985|sc-291|sc-365083|sc-514429|sc-22827|
Rabbit polyclonal NFATC3 antibody
|Catalogue No.|| |
Recombinant protein of human NFATC3
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 115kDa/Observed: Refer to figures
NFATC3 antibody was tube-contained.
NFATC3 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
NFAT4 antibody, NFATX antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2.
|Protein tissue specificity|| |
Isoform 1 is predominantly expressed in thymus and is also found in peripheral blood leukocytes and kidney. Isoform 2 is predominantly expressed in skeletal muscle and is also found in thymus, kidney, testis, spleen, prostate, ovary, small intestine, heart, placenta and pancreas. Isoform 3 is expressed in thymus and kidney. Isoform 4 is expressed in thymus and skeletal muscle.
|Protein sequence and domain|| |
Rel Similarity Domain (RSD) allows DNA-binding and cooperative interactions with AP1 factors.Contains 1 RHD (Rel-like) domain.
|Protein post-translational modifications|| |
Phosphorylated by NFATC-kinase; dephosphorylated by calcineurin.
|Protein cellular localization|| |
Cytoplasm . Nucleus . Note: Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene.
AntibodyPlus can customize NFATC3 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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