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Rabbit polyclonal NFATC3 antibody (A6666)
$69.00–$259.00
Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal NFATC3 antibody (A6666)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
Recommended dilution:
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Image descriptions:
Click or hover above images to see image description for Rabbit polyclonal NFATC3 antibody.
Alternative names:
Check alternative names for the antibody
ExpandNFAT4 antibody, NFATX antibody
C80703 antibody|cytoplasmic 3 antibody|D8Ertd281e antibody|NF AT4 antibody|NF ATc3 antibody|NF-AT4 antibody|NF-ATc3 antibody|NFAC3_HUMAN antibody|NFATc3 antibody|NFATx antibody|Nuclear factor of activated T cells, cytoplasmic 3 antibody|nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 antibody|Nuclear factor of activated T-cells antibody|T cell transcription factor NFAT4 antibody|T-cell transcription factor NFAT4 antibody|Anti-NFAT4 antibody (ab93628)
SCBT cat No: sc-23814|sc-1152|sc-8405|sc-8321|sc-271127|sc-271597|sc-1153|sc-271091|sc-13036|sc-32989|sc-32985|sc-291|sc-365083|sc-514429|sc-22827|
| Name | Rabbit polyclonal NFATC3 antibody |
|---|---|
| Catalogue No. | A6666 |
| Reactivity | Human, Mouse |
| Immunogen | Recombinant protein of human NFATC3 |
| Host | Rabbit |
| Applications | WB, IHC, IF |
| Recommended dilution | WB 1:500 – 1:2000 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Molecular weight | Predicted: 115kDa/Observed: Refer to figures |
| Formulation | NFATC3 antibody was tube-contained. |
| Purification | NFATC3 antibody was purified using affinity purification. |
| Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
| Alternative antibody names | NFAT4 antibody, NFATX antibody |
| Database links | Human UniProt/Swiss-Prot:Q12968 |
| Protein names | NFAT4, NFATX |
| Protein function | Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2. |
| Protein tissue specificity | Isoform 1 is predominantly expressed in thymus and is also found in peripheral blood leukocytes and kidney. Isoform 2 is predominantly expressed in skeletal muscle and is also found in thymus, kidney, testis, spleen, prostate, ovary, small intestine, heart, placenta and pancreas. Isoform 3 is expressed in thymus and kidney. Isoform 4 is expressed in thymus and skeletal muscle. |
| Protein sequence and domain | Rel Similarity Domain (RSD) allows DNA-binding and cooperative interactions with AP1 factors.Contains 1 RHD (Rel-like) domain. |
| Protein post-translational modifications | Phosphorylated by NFATC-kinase; dephosphorylated by calcineurin. |
| Protein cellular localization | Cytoplasm . Nucleus . Note: Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription. |
| Background | The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. |
| Research area | All research areas>Transcription Regulators>NFAT |
| Note | AntibodyPlus can customize NFATC3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
| Product type | Primary antibody |
| Supplier | ABclonal Inc. |
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