Rabbit polyclonal NFATC3 antibody (A6666)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal NFATC3 antibody (A6666)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal NFATC3 antibody.

Alternative names:

Check alternative names for the antibody

Expand

NFAT4 antibody, NFATX antibody
C80703 antibody|cytoplasmic 3 antibody|D8Ertd281e antibody|NF AT4 antibody|NF ATc3 antibody|NF-AT4 antibody|NF-ATc3 antibody|NFAC3_HUMAN antibody|NFATc3 antibody|NFATx antibody|Nuclear factor of activated T cells, cytoplasmic 3 antibody|nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 antibody|Nuclear factor of activated T-cells antibody|T cell transcription factor NFAT4 antibody|T-cell transcription factor NFAT4 antibody|Anti-NFAT4 antibody (ab93628)

SCBT cat No: sc-23814|sc-1152|sc-8405|sc-8321|sc-271127|sc-271597|sc-1153|sc-271091|sc-13036|sc-32989|sc-32985|sc-291|sc-365083|sc-514429|sc-22827|

Name

Rabbit polyclonal NFATC3 antibody

Catalogue No.

A6666

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human NFATC3

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 115kDa/Observed: Refer to figures

Formulation

NFATC3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

NFATC3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NFAT4 antibody, NFATX antibody

Database links

Human UniProt/Swiss-Prot:Q12968

Protein names

NFAT4, NFATX

Protein function

Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2.

Protein tissue specificity

Isoform 1 is predominantly expressed in thymus and is also found in peripheral blood leukocytes and kidney. Isoform 2 is predominantly expressed in skeletal muscle and is also found in thymus, kidney, testis, spleen, prostate, ovary, small intestine, heart, placenta and pancreas. Isoform 3 is expressed in thymus and kidney. Isoform 4 is expressed in thymus and skeletal muscle.

Protein sequence and domain

Rel Similarity Domain (RSD) allows DNA-binding and cooperative interactions with AP1 factors.Contains 1 RHD (Rel-like) domain.

Protein post-translational modifications

Phosphorylated by NFATC-kinase; dephosphorylated by calcineurin.

Protein cellular localization

Cytoplasm . Nucleus . Note: Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.

Background

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene.

Research area

All research areas>Transcription Regulators>NFAT
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize NFATC3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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