No products in the cart.
Rabbit Polyclonal NFKBIZ antibody (A10492)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit Polyclonal NFKBIZ antibody.
Check alternative names for the antibodyExpand
FLJ30225 antibody|FLJ34463 antibody|I-kappa-B-zeta antibody|Ikappa B zeta antibody|IkappaB zeta antibody|IkappaBzeta antibody|IkB-zeta antibody|IKBZ antibody|IKBZ_HUMAN antibody|IKBzeta antibody|IL-1 inducible nuclear ankyrin-repeat protein antibody|INAP antibody|MAIL antibody|MAIL protein antibody|Molecule possessing ankyrin repeats induced by lipopolysaccharide antibody|NF-kappa-B inhibitor zeta antibody|NFKBIZ antibody|Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor zeta antibody|Anti-IKB zeta antibody (ab168850)
SCBT cat No: sc-33421|sc-66935|sc-33419|
Rabbit Polyclonal NFKBIZ antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human NFKBIZ
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
NFKBIZ antibody was tube-contained.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/Q9BYH8">Q9BYH8</a>
|Protein function|| |
Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. May promote apoptosis (By similarity).
|Protein tissue specificity|| |
Expressed at high levels in peripheral blood leukocytes and lung, at moderate levels in liver, placenta, and at low levels in spleen, kidney, skeletal muscle and heart.
|Protein sequence and domain|| |
Contains 7 ANK repeats.
|Protein cellular localization|| |
Nucleus . Note=Aggregated in dot-like structures. Colocalizes with NCOR2.
AntibodyPlus can customize NFKBIZ antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: