Rabbit polyclonal NME4 antibody (A8350)


Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal NME4 antibody (A8350)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


NDPK-D antibody, NM23H4 antibody, nm23-H4 antibody
metastatic inhibition factor NM23H4 antibody|mitochondrial antibody|NDK antibody|NDKM_HUMAN antibody|NDP kinase antibody|NDP kinase D antibody|NDP kinase, mitochondrial antibody|NDPK D antibody|NDPKD antibody|nm23 H4 antibody|nm23-H4 antibody|NM23D antibody|NM23H4 antibody|Nm23M4 antibody|NME/NM23 nucleoside diphosphate kinase 4 antibody|NME4 antibody|Non metastatic cells 4 protein expressed in antibody|Non metastatic protein 23, homolog 4 antibody|Nucleoside diphosphate kinase D antibody|Nucleoside diphosphate kinase, mitochondrial antibody|Nucleoside diphosphate kinase, mitochondrial antibody|Anti-NME4 antibody – C-terminal (ab71623)

SCBT cat No: sc-99071|


Rabbit polyclonal NME4 antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human NME4





Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100







Molecular weight

Predicted: 21kDa/Observed: Refer to figures


NME4 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


NME4 antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NDPK-D antibody, NM23H4 antibody, nm23-H4 antibody

Database links

Human UniProt/Swiss-Prot:O00746

Protein names

NDPK-D, NM23H4, nm23-H4

Protein function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Through the catalyzed exchange of gamma-phosphate between di- and triphosphonucleosides participates in regulation of intracellular nucleotide homeostasis . Binds to anionic phospholipids, predominantly to cardiolipin; the binding inhibits its phosphotransfer activity . Acts as mitochondria-specific NDK; its association with cardiolipin-containing mitochondrial inner membrane is coupled to respiration suggesting that ADP locally regenerated in the mitochondrion innermembrane space by its activity is directly taken up via ANT ADP/ATP translocase into the matrix space to stimulate respiratory ATP regeneration . Proposed to increase GTP-loading on dynamin-related GTPase OPA1 in mitochondria . In vitro can induce liposome cross-linking suggesting that it can cross-link inner and outer membranes to form contact sites, and promotes intermembrane migration of anionic phosphoplipids. Promotes the redistribution of cardiolipin between the mitochondrial inner membrane and outer membrane which is implicated in pro-apoptotic signaling .

Protein tissue specificity

Widely distributed. Found at very high levels in prostate, heart, liver, small intestine, and skeletal muscle tissues, and in low amounts in the brain and in blood leukocytes.

Protein sequence and domain

Belongs to the NDK family.

Protein cellular localization

Mitochondrion intermembrane space ; Peripheral membrane protein. Mitochondrion matrix . Note: Predominantly localized in the mitochondrion intermembrane space . Colocalizes with OPA1 in mitochondria .


The nucleoside diphosphate (NDP) kinases (EC are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. The enzymes are products of the nm23 gene family, which includes NME4 (Milon et al., 1997

Research area

All research areas>Kinases and Phosphatases>nm23-H
(View all antibody categories related to Kinases and Phosphatases)


AntibodyPlus can customize NME4 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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