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Rabbit polyclonal NOX5 antibody (A7136)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal NOX5 antibody.
Check alternative names for the antibodyExpand
MGC149776 antibody|MGC149777 antibody|NADPH oxidase 5 antibody|NADPH oxidase EFhand calcium binding domain 5 antibody|NOX5 antibody|NOX5_HUMAN antibody|Anti-NOX5 antibody – C-terminal (ab191010)
SCBT cat No: sc-67006|sc-34707|
Rabbit polyclonal NOX5 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human NOX5
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 86kDa/Observed: Refer to figures
NOX5 antibody was tube-contained.
NOX5 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis. Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin.
|Protein tissue specificity|| |
Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes. Isoform v1 is expressed in spleen. Isoform v2 is expressed in testis. Also detected in ovary, placenta, pancreas, cardiac fibroblasts. Expressed in B-cells and prostate malignant cells. Isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells. Isoform v2 and isoform v4 are expressed in endothelial cells. Isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells. Isoform v2 and isoform v5 are expressed in microvascular endothelial cells (at protein level).
|Protein sequence and domain|| |
Isoform v1 and isoform v2 of this protein have four functional EF-hand calcium-binding domains. Isoform v3 and isoform v4 have the third EF-hand domain interrupted by an insert.Contains 4 EF-hand domains.; Contains 1 FAD-binding FR-type domain.; Contains 1 ferric oxidoreductase domain.
|Protein cellular localization|| |
Membrane ; Multi-pass membrane protein .; Isoform v2: Endoplasmic reticulum.; Isoform v5: Endoplasmic reticulum.
This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
AntibodyPlus can customize NOX5 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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