Rabbit polyclonal NSFL1C antibody (A6677)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal NSFL1C antibody (A6677)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal NSFL1C antibody.

Alternative names:

Check alternative names for the antibody

Expand

P47 antibody, UBX1 antibody, UBXD10 antibody, UBXN2C antibody, dJ776F14.1 antibody
DJ776F14.1 antibody|MGC3347 antibody|NSF1C_HUMAN antibody|NSFL1 (p97) cofactor (p47) antibody|NSFL1 cofactor p47 antibody|NSFL1C antibody|OTTHUMP00000029972 antibody|OTTHUMP00000029974 antibody|p47 antibody|P47 protein antibody|p97 cofactor p47 antibody|SHP1 homolog antibody|UBX domain protein 2C antibody|UBX domain-containing protein 2C antibody|UBX1 antibody|UBXD10 antibody|UBXN2C antibody|Anti-NSFL1C antibody (ab95963)

SCBT cat No: sc-365215|sc-86190|sc-376614|

Name

Rabbit polyclonal NSFL1C antibody

Catalogue No.

A6677

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human NSFL1C

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 40kDa/Observed: Refer to figures

Formulation

NSFL1C antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

NSFL1C antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

P47 antibody, UBX1 antibody, UBXD10 antibody, UBXN2C antibody, dJ776F14.1 antibody

Database links

Human UniProt/Swiss-Prot:Q9UNZ2

Protein names

P47, UBX1, UBXD10, UBXN2C, dJ776F14.1

Protein function

Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity). Inhibits the activity of CTSL (in vitro).

Protein sequence and domain

Belongs to the NSFL1C family.; Contains 1 SEP domain.; Contains 1 UBX domain.

Protein post-translational modifications

Phosphorylated during mitosis. Phosphorylation inhibits interaction with Golgi membranes and is required for the fragmentation of the Golgi stacks during mitosis (By similarity).

Protein cellular localization

Nucleus . Golgi apparatus, Golgi stack . Chromosome . Note: Predominantly nuclear in interphase cells. Bound to the axial elements of sex chromosomes in pachytene spermatocytes. A small proportion of the protein is cytoplasmic, associated with Golgi stacks (By similarity).

Background

N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.

Note

AntibodyPlus can customize NSFL1C antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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