Rabbit polyclonal NT5E antibody (A2029)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal NT5E antibody (A2029)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal NT5E antibody.

Alternative names:

Check alternative names for the antibody

Expand

CD73 antibody, E5NT antibody, NT antibody, NT5 antibody, NTE antibody, eN antibody, Ent antibody
5′ NT antibody|5′ nucleotidase (CD73) antibody|5′ nucleotidase precursor antibody|5′ nucleotidase, ecto antibody|5′ nucleotidase, ecto (CD73) antibody|5′-NT antibody|5′-nucleotidase antibody|5NTD_HUMAN antibody|CD73 antibody|CD73 antigen antibody|E5NT antibody|Ecto 5′ nucleotidase antibody|Ecto-5′-nucleotidase antibody|eN antibody|eNT antibody|NT antibody|NT5 antibody|NT5E antibody|NTE antibody|Purine 5 Prime Nucleotidase antibody|Anti-CD73 antibody [7G2] (ab54217)

SCBT cat No: sc-130006|sc-14684|sc-398260|sc-25603|sc-32299|sc-14682|

Name

Rabbit polyclonal NT5E antibody

Catalogue No.

A2029

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human NT5E

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 63kDa/Observed: Refer to Figures

Formulation

NT5E antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

NT5E antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CD73 antibody, E5NT antibody, NT antibody, NT5 antibody, NTE antibody, eN antibody, Ent antibody

Database links

Human UniProt/Swiss-Prot:P21589

Protein names

CD73, E5NT, NT, NT5, NTE, eN, Ent

Protein function

Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.

Protein sequence and domain

Belongs to the 5′-nucleotidase family.

Protein cellular localization

Cell membrane; Lipid-anchor, GPI-anchor.

Background

Ecto-5’nucleotidase (NT5E, also called CD73) is a 70 kDa glycosyl phosphatidylinositol-anchored membrane-bound glycoprotein that catalyzes the hydrolysis of extracellular nucleoside monophosphates into bioactive nucleoside (1). NT5E catalyzes the terminal step of extracellular adenosine formation from adenosine-monophosphate, therefore driving the regulation of extracellular adenosine levels and the downstream activation of the four G protein-coupled adenosine receptors (2). Binding of hypoxia-inducible factor (HIF-1) to the NT5E gene promotor leads to upregulation of NT5E during hypoxia (3). NT5E biological roles span from lymphocyte adhesion (4,5), to fibrosis (6), to regulation of nociception (7,8).

Research area

All research areas>Lymphocyte Signaling>CD73
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize NT5E antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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