Rabbit polyclonal NTMT1 antibody (A7098)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal NTMT1 antibody (A7098)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

NRMT antibody, NTM1A antibody, AD-003 antibody, HOMT1A antibody, C9orf32 antibody, METTL11A antibody
AD 003 antibody|Alpha N-terminal protein methyltransferase 1A antibody|C9orf32 antibody|Chromosome 9 open reading frame 32 antibody|Methyltransferase like 11A antibody|Methyltransferase-like protein 11A antibody|Mettl11a antibody|N-terminal RCC1 methyltransferase antibody|NRMT antibody|NTM1A antibody|NTM1A_HUMAN antibody|NTMT1 antibody|X-Pro-Lys N-terminal protein methyltransferase 1A antibody|Anti-METTL11A antibody (ab102664)

SCBT cat No: sc-243462|

Name

Rabbit polyclonal NTMT1 antibody

Catalogue No.

A7098

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human NTMT1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 25kDa/Observed: Refer to figures

Formulation

NTMT1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

NTMT1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NRMT antibody, NTM1A antibody, AD-003 antibody, HOMT1A antibody, C9orf32 antibody, METTL11A antibody

Database links

Human UniProt/Swiss-Prot:Q9BV86

Protein names

NRMT, NTM1A, AD-003, HOMT1A, C9orf32, METTL11A

Protein function

Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.

Protein sequence and domain

Belongs to the methyltransferase superfamily. NTM1 family.

Protein cellular localization

Nucleus . Note: Predominantly nuclear.

Background

The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1; MIM 179710). METTL11A enzyme alpha-N-methylates other protein targets such as SET (MIM 600960) and RB (MIM 180200).

Note

AntibodyPlus can customize NTMT1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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