Rabbit polyclonal NTSR1 antibody (A3054)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal NTSR1 antibody (A3054)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal NTSR1 antibody.

Alternative names:

Check alternative names for the antibody

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NTR antibody
High affinity levocabastine insensitive neurotensin receptor antibody|Neurotensin receptor 1 (high affinity) antibody|Neurotensin receptor type 1 antibody|NT R 1 antibody|NTR antibody|NTR1 antibody|NTR1_HUMAN antibody|NTRH antibody|NTRR antibody|NTSR 1 antibody|Anti-Neurotensin Receptor 1 antibody (ab117592)

SCBT cat No: sc-374492|sc-7596|

Name

Rabbit polyclonal NTSR1 antibody

Catalogue No.

A3054

Reactivity

Human

Immunogen

A synthetic peptide of human NTSR1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 46kDa/Observed: Refer to Figures

Formulation

NTSR1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

NTSR1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NTR antibody

Database links

Human UniProt/Swiss-Prot:P30989

Protein names

NTR

Protein function

G-protein coupled receptor for the tridecapeptide neurotensin (NTS) . Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis .

Protein tissue specificity

Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.

Protein sequence and domain

The ligand binding pocket consists mainly of extracellular loops ECL2 and ECL3, as well as transmembrane regions TM6 and TM7.Belongs to the G-protein coupled receptor 1 family. Neurotensin receptor subfamily. NTSR1 sub-subfamily.

Protein post-translational modifications

N-gycosylated.; Palmitoylated; this is required for normal localization at membrane rafts and normal GNA11-mediated activation of down-stream signaling cascades. The palmitoylation level increases in response to neurotensin treatment.

Protein cellular localization

Cell membrane ; Multi-pass membrane protein . Membrane raft . Note: Palmitoylation is required for localization at CAV1-enriched membrane rafts.

Background

Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion.

Research area

All research areas>Neurobiology>NTR
(View all antibody categories related to Neurobiology)

Note

AntibodyPlus can customize NTSR1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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