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Rabbit polyclonal NTSR1 antibody (A3054)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal NTSR1 antibody.
Check alternative names for the antibodyExpand
High affinity levocabastine insensitive neurotensin receptor antibody|Neurotensin receptor 1 (high affinity) antibody|Neurotensin receptor type 1 antibody|NT R 1 antibody|NTR antibody|NTR1 antibody|NTR1_HUMAN antibody|NTRH antibody|NTRR antibody|NTSR 1 antibody|Anti-Neurotensin Receptor 1 antibody (ab117592)
SCBT cat No: sc-374492|sc-7596|
Rabbit polyclonal NTSR1 antibody
|Catalogue No.|| |
A synthetic peptide of human NTSR1
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 46kDa/Observed: Refer to Figures
NTSR1 antibody was tube-contained.
NTSR1 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
G-protein coupled receptor for the tridecapeptide neurotensin (NTS) . Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis .
|Protein tissue specificity|| |
Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.
|Protein sequence and domain|| |
The ligand binding pocket consists mainly of extracellular loops ECL2 and ECL3, as well as transmembrane regions TM6 and TM7.Belongs to the G-protein coupled receptor 1 family. Neurotensin receptor subfamily. NTSR1 sub-subfamily.
|Protein post-translational modifications|| |
N-gycosylated.; Palmitoylated; this is required for normal localization at membrane rafts and normal GNA11-mediated activation of down-stream signaling cascades. The palmitoylation level increases in response to neurotensin treatment.
|Protein cellular localization|| |
Cell membrane ; Multi-pass membrane protein . Membrane raft . Note: Palmitoylation is required for localization at CAV1-enriched membrane rafts.
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion.
AntibodyPlus can customize NTSR1 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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