Rabbit polyclonal NUP62 antibody (A2499)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal NUP62 antibody (A2499)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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p62 antibody, IBSN antibody, SNDI antibody
62 kDa nucleoporin antibody|DKFZp547L134 antibody|FLJ20822 antibody|FLJ43869 antibody|IBSN antibody|MGC841 antibody|Nuclear pore glycoprotein p62 antibody|nucleoporin 62kDa antibody|Nucleoporin Nup62 antibody|nucleoporin p62 antibody|nucleoporin p62KD antibody|NUP62 antibody|NUP62 protein antibody|p62 antibody|SNDI antibody|Anti-Nucleoporin p62 antibody (ab96134)

SCBT cat No: sc-6078|

Name

Rabbit polyclonal NUP62 antibody

Catalogue No.

A2499

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human NUP62

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 53kDa/Observed: Refer to Figures

Formulation

NUP62 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

NUP62 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

p62 antibody, IBSN antibody, SNDI antibody

Database links

Human UniProt/Swiss-Prot:P37198

Protein names

p62, IBSN, SNDI

Protein function

Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex.

Protein sequence and domain

Contains F-X-F-G repeats.Belongs to the nucleoporin NSP1/NUP62 family.

Protein post-translational modifications

O-glycosylated. Contains about 10 N-acetylglucosamine side chain sites predicted for the entire protein, amongst which only one in the C-terminal.; The the inner channel of the NPC has a different redox environment from the cytoplasm and allows the formation of interchain disulfide bonds between some nucleoporins, the significant increase of these linkages upon oxidative stress reduces the permeability of the NPC.

Protein cellular localization

Nucleus, nuclear pore complex. Cytoplasm, cytoskeleton, spindle pole. Note: Central region of the nuclear pore, within the transporter. During mitotic cell division, it associates with the poles of the mitotic spindle.

Background

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform.

Note

AntibodyPlus can customize NUP62 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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Antibody customer reviews & validation data - 137

Validation data ID: 137

Submission date: 2017-03-02

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Figure description:

IF analysis using HMGB1&NUP62

Product name

HMGB1;NUP62

Product catalog No.

A2553;A2499

Product type

Primary antibody

Supplier

St John's Laboratory Ltd

Application type

Immunofluorescence (IF)

Antibody specificity rating

Good

Antibody overall rating

Good

Your comments

hope my work will helpful

Detailed protocol

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