Rabbit polyclonal OGDH antibody (A6391)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal OGDH antibody (A6391)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal OGDH antibody.

Alternative names:

Check alternative names for the antibody

Expand

E1k antibody, OGDC antibody, AKGDH antibody
2 oxoglutarate dehydrogenase antibody|2 oxoglutarate dehydrogenase complex component E1 antibody|2 oxoglutarate dehydrogenase mitochondrial antibody|2-oxoglutarate dehydrogenase antibody|2-oxoglutarate dehydrogenase complex component E1 antibody|AKGDH antibody|Alpha ketoglutarate dehydrogenase antibody|Alpha-ketoglutarate dehydrogenase antibody|E1k antibody|mitochondrial antibody|ODO1_HUMAN antibody|OGDC antibody|OGDC E1 antibody|OGDC-E1 antibody|OGDH antibody|Oxoglutarate (alpha ketoglutarate) dehydrogenase (lipoamide) antibody|Oxoglutarate decarboxylase antibody|Oxoglutarate dehydrogenase (lipoamide) antibody|Oxoglutarate dehydrogenase (succinyl transferring) antibody|Anti-OGDH antibody – C-terminal (ab137773)

SCBT cat No: sc-49589|sc-49590|sc-49591|sc-67238|

Name

Rabbit polyclonal OGDH antibody

Catalogue No.

A6391

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human OGDH

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 115kDa/Observed: Refer to Figures

Formulation

OGDH antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

OGDH antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

E1k antibody, OGDC antibody, AKGDH antibody

Database links

Human UniProt/Swiss-Prot:Q02218

Protein names

E1k, OGDC, AKGDH

Protein function

The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).

Protein sequence and domain

Belongs to the alpha-ketoglutarate dehydrogenase family.

Protein cellular localization

Mitochondrion matrix.

Background

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Note

AntibodyPlus can customize OGDH antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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