Rabbit polyclonal ORC4 antibody (A7705)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ORC4 antibody (A7705)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ORC4L antibody, ORC4P antibody
Origin recognition complex, subunit 4, S. cerevisiae, homolog of antibody|FLJ46668 antibody|HSORC4 antibody|ORC 4 antibody|ORC 4L antibody|ORC 4P antibody|ORC4 antibody|ORC4_HUMAN antibody|ORC4L antibody|ORC4L protein antibody|ORC4P antibody|Origin recognition complex subunit 4 (yeast homolog) like antibody|Origin recognition complex subunit 4 antibody|Origin recognition complex subunit 4 like (yeast) antibody|Origin recognition complex subunit 4 like antibody|origin recognition complex, subunit 4 homolog antibody|Origin recognition complex, subunit 4, S. cerevisiae, homolog-like antibody|Anti-ORC4L antibody – ChIP Grade (ab9641)

SCBT cat No: sc-136331|sc-19726|sc-393985|sc-398455|sc-20634|sc-19725|

Name

Rabbit polyclonal ORC4 antibody

Catalogue No.

A7705

Reactivity

Human

Immunogen

Recombinant protein of human ORC4

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 50kDa/Observed: Refer to figures

Formulation

ORC4 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ORC4 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ORC4L antibody, ORC4P antibody

Database links

Human UniProt/Swiss-Prot:O43929

Protein names

ORC4L, ORC4P

Protein function

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

Protein sequence and domain

Belongs to the ORC4 family.

Protein cellular localization

Nucleus.

Background

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

Research area

All research areas>Transcription Regulators>ORC
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize ORC4 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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