Rabbit polyclonal ORC6 antibody (A7966)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ORC6 antibody (A7966)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ORC6L antibody
ORC 6 antibody|Orc6 antibody|ORC6_HUMAN antibody|ORC6L antibody|Origin recognition complex subunit 6 antibody|origin recognition complex subunit 6 homolog like antibody|origin recognition complex subunit 6 homolog like (yeast) antibody|origin recognition complex subunit 6 like (yeast) antibody|Anti-ORC6L antibody (ab88686)

SCBT cat No: sc-81646|sc-32735|sc-390490|sc-20636|

Name

Rabbit polyclonal ORC6 antibody

Catalogue No.

A7966

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ORC6

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 28kDa/Observed: Refer to figures

Formulation

ORC6 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ORC6 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ORC6L antibody

Database links

Human UniProt/Swiss-Prot:Q9Y5N6

Protein names

ORC6L

Protein function

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Does not bind histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

Protein sequence and domain

Belongs to the ORC6 family.

Protein cellular localization

Nucleus.

Background

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

Research area

All research areas>Transcription Regulators>ORC
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize ORC6 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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