Rabbit polyclonal PAIP1 antibody (A6042)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PAIP1 antibody (A6042)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:1000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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MGC12360 antibody|OTTHUMP00000221601 antibody|OTTMUSP00000026880 antibody|PABC1 interacting protein 1 antibody|PABP interacting protein 1 antibody|PABP-interacting protein 1 antibody|PAIP 1 antibody|PAIP-1 antibody|Paip1 antibody|PAIP1_HUMAN antibody|Poly(A) binding protein interacting protein 1 antibody|Poly(A)-binding protein-interacting protein 1 antibody|Polyadenylate binding protein interacting protein 1 antibody|Polyadenylate-binding protein-interacting protein 1 antibody|Anti-PAIP1 antibody [EPR13259] (ab181359)

SCBT cat No: sc-365687|sc-365188|

Name

Rabbit polyclonal PAIP1 antibody

Catalogue No.

A6042

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PAIP1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:1000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 53kDa/Observed: Refer to Figures

Formulation

PAIP1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PAIP1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q9H074

Protein function

Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Protein sequence and domain

Only the PABPC1-interacting motif-1 (PAM1) stimulates translation initiation.Contains 1 MIF4G domain.

Protein cellular localization

Cytoplasm .

Background

The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.

Note

AntibodyPlus can customize PAIP1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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