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Rabbit polyclonal PAIP1 antibody (A6042)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:1000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal PAIP1 antibody.
Check alternative names for the antibodyExpand
MGC12360 antibody|OTTHUMP00000221601 antibody|OTTMUSP00000026880 antibody|PABC1 interacting protein 1 antibody|PABP interacting protein 1 antibody|PABP-interacting protein 1 antibody|PAIP 1 antibody|PAIP-1 antibody|Paip1 antibody|PAIP1_HUMAN antibody|Poly(A) binding protein interacting protein 1 antibody|Poly(A)-binding protein-interacting protein 1 antibody|Polyadenylate binding protein interacting protein 1 antibody|Polyadenylate-binding protein-interacting protein 1 antibody|Anti-PAIP1 antibody [EPR13259] (ab181359)
SCBT cat No: sc-365687|sc-365188|
Rabbit polyclonal PAIP1 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human PAIP1
|Recommended dilution|| |
WB 1:500 – 1:1000
|Molecular weight|| |
Predicted: 53kDa/Observed: Refer to Figures
PAIP1 antibody was tube-contained.
PAIP1 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
|Protein sequence and domain|| |
Only the PABPC1-interacting motif-1 (PAM1) stimulates translation initiation.Contains 1 MIF4G domain.
|Protein cellular localization|| |
The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
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|Product type|| |
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