Rabbit polyclonal PAX4 antibody (A5414)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PAX4 antibody (A5414)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PAX4 antibody.

Alternative names:

Check alternative names for the antibody

Expand

KPD antibody, MODY9 antibody
KPD antibody|MGC129960 antibody|MODY9 antibody|Paired box 4 antibody|Paired box gene 4 antibody|paired box homeotic gene 4 antibody|Paired box protein Pax-4 antibody|Paired domain gene 4 antibody|Pax4 antibody|PAX4_HUMAN antibody|Anti-PAX4 antibody (ab42450)

SCBT cat No: sc-27832|

Name

Rabbit polyclonal PAX4 antibody

Catalogue No.

A5414

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PAX4

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 38kDa/Observed: Refer to figures

Formulation

PAX4 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PAX4 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

KPD antibody, MODY9 antibody

Database links

Human UniProt/Swiss-Prot:O43316

Protein names

KPD, MODY9

Protein function

Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.

Protein sequence and domain

Belongs to the paired homeobox family.; Contains 1 homeobox DNA-binding domain.; Contains 1 paired domain.

Protein cellular localization

Nucleus.

Background

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.

Research area

All research areas>Homeodomain Proteins>Pax
(View all antibody categories related to Homeodomain Proteins)

Note

AntibodyPlus can customize PAX4 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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