Rabbit polyclonal PCBD1 antibody (A6392)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PCBD1 antibody (A6392)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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PCD antibody, PHS antibody, DCOH antibody, PCBD antibody
4 alpha hydroxy tetrahydropterin dehydratase antibody|4-alpha-hydroxy-tetrahydropterin dehydratase antibody|6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) antibody|6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha antibody|DCoH antibody|Dimerization cofactor of hepatic nuclear factor 1 alpha antibody|Dimerization cofactor of hepatocyte nuclear factor 1 alpha antibody|Dimerization cofactor of hepatocyte nuclear factor 1-alpha antibody|Dimerization cofactor of HNF1 antibody|Dimerizing cofactor for HNF1 antibody|PCBD 1 antibody|PCBD antibody|PCBD1 antibody|PCD antibody|Phenylalanine hydroxylase stimulating protein antibody|Phenylalanine hydroxylase-stimulating protein antibody|PHS antibody|PHS_HUMAN antibody|Pterin 4 alpha carbinolamine dehydratase antibody|Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) antibody|Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha antibody|Pterin carbinolamine dehydratase antibody|Pterin-4-alpha-carbinolamine dehydratase antibody|Anti-PCBD1 antibody [EPR9760(B)] (ab138518)

SCBT cat No: sc-100488|

Name

Rabbit polyclonal PCBD1 antibody

Catalogue No.

A6392

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PCBD1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 12kDa/Observed: Refer to Figures

Formulation

PCBD1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PCBD1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PCD antibody, PHS antibody, DCOH antibody, PCBD antibody

Database links

Human UniProt/Swiss-Prot:P61457

Protein names

PCD, PHS, DCOH, PCBD

Protein function

Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity.

Protein sequence and domain

Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Protein cellular localization

Cytoplasm. Nucleus. Note: Cytoplasmic and/or nuclear.

Background

This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.

Note

AntibodyPlus can customize PCBD1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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