Rabbit polyclonal PCDH15 antibody (A10086)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PCDH15 antibody (A10086)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

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Alternative names:

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SCBT cat No:

Name

Rabbit polyclonal PCDH15 antibody

Catalogue No.

A10086

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PCDH15

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 216kDa/Observed: Refer to figures

Formulation

PCDH15 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PCDH15 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q96QU1

Protein function

Calcium-dependent cell-adhesion protein. Essential for maintenance of normal retinal and cochlear function.

Protein tissue specificity

Expressed in brain, lung, kidney, spleen and testis. Found also in the inner and outer synaptic layers, and the nerve fiber layer in adult and fetal retinas. Found in the supporting cells, outer sulcus cells and spiral ganglion of fetal cochlea. Expressed in cytotoxic tumor-derived T- and NK-cell lines as well as biopsies of nasal NK/T-cell lymphomas. Not detected in normal or in vitro activated peripheral blood cells, CD4 or CD8 lymphocytes or NK cells. Isoform 3 is expressed in brain, heart, cerebellum and kidney. CD1 isoforms, such as isoform 1, have a limited pattern of expression and is detected in testis, retina and cochlea. CD2 isoforms, such as isoforms 4 and 5, are expressed in heart, kidney, thymus, spleen, testis, retina and cochlea. CD3 isoforms, such as isoform 6, are widely expressed.

Protein sequence and domain

Cadherin repeats 1 and 2 mediate calcium-dependent heterophilic interaction with CDH23.; Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.Contains 11 cadherin domains.

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein . Note: Efficient localization to the plasma membrane requires the presence of LHFPL5.; Isoform 3: Secreted.

Research area

All research areas>Cell Adhesion Proteins>PCDH
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize PCDH15 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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