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Rabbit polyclonal PCDH15 antibody (A10086)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal PCDH15 antibody.
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SCBT cat No:
Rabbit polyclonal PCDH15 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human PCDH15
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 216kDa/Observed: Refer to figures
PCDH15 antibody was tube-contained.
PCDH15 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Calcium-dependent cell-adhesion protein. Essential for maintenance of normal retinal and cochlear function.
|Protein tissue specificity|| |
Expressed in brain, lung, kidney, spleen and testis. Found also in the inner and outer synaptic layers, and the nerve fiber layer in adult and fetal retinas. Found in the supporting cells, outer sulcus cells and spiral ganglion of fetal cochlea. Expressed in cytotoxic tumor-derived T- and NK-cell lines as well as biopsies of nasal NK/T-cell lymphomas. Not detected in normal or in vitro activated peripheral blood cells, CD4 or CD8 lymphocytes or NK cells. Isoform 3 is expressed in brain, heart, cerebellum and kidney. CD1 isoforms, such as isoform 1, have a limited pattern of expression and is detected in testis, retina and cochlea. CD2 isoforms, such as isoforms 4 and 5, are expressed in heart, kidney, thymus, spleen, testis, retina and cochlea. CD3 isoforms, such as isoform 6, are widely expressed.
|Protein sequence and domain|| |
Cadherin repeats 1 and 2 mediate calcium-dependent heterophilic interaction with CDH23.; Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.Contains 11 cadherin domains.
|Protein cellular localization|| |
Cell membrane ; Single-pass type I membrane protein . Note: Efficient localization to the plasma membrane requires the presence of LHFPL5.; Isoform 3: Secreted.
AntibodyPlus can customize PCDH15 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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