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Rabbit polyclonal PCDHA12 antibody (A8501)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:100
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
KIAA0345 like 2 antibody|MGC138485 antibody|MGC141932 antibody|PCDAC_HUMAN antibody|PCDH alpha 12 antibody|PCDH alpha12 antibody|PCDH-alpha-12 antibody|PCDHA12 antibody|Protocadherin alpha 12 antibody|Protocadherin alpha-12 antibody|Anti-PCDHA12 antibody (ab129410)
SCBT cat No: sc-109753|
Rabbit polyclonal PCDHA12 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human PCDHA12
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 102kDa/Observed: Refer to figures
PCDHA12 antibody was tube-contained.
PCDHA12 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
|Protein sequence and domain|| |
Contains 6 cadherin domains.
|Protein cellular localization|| |
Cell membrane ; Single-pass type I membrane protein .
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
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|Product type|| |
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