Rabbit polyclonal PCK1 antibody (A2036)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PCK1 antibody (A2036)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:1000 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PCK1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

MGC22652 antibody, PEPCK-C antibody, PEPCK1 antibody, PEPCKC antibody
cytosolic [GTP] antibody|GTP antibody|PCK1 antibody|PCKGC_HUMAN antibody|PEP carboxykinase antibody|PEPCK-C antibody|PEPCK1 antibody|PEPCKC antibody|Phosphoenolpyruvate carboxykinase 1 (soluble) antibody|Phosphoenolpyruvate carboxykinase 1 antibody|Phosphoenolpyruvate carboxykinase antibody|Phosphoenolpyruvate carboxykinase, cytosolic [GTP] antibody|Phosphoenolpyruvate carboxykinase, cytosolic antibody|Phosphoenolpyruvate carboxylase antibody|Phosphopyruvate carboxylase antibody|Anti-PCK1 antibody (ab28455)

SCBT cat No: sc-135279|

Name

Rabbit polyclonal PCK1 antibody

Catalogue No.

A2036

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human PCK1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:1000 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 69kDa/Observed: Refer to Figures

Formulation

PCK1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PCK1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MGC22652 antibody, PEPCK-C antibody, PEPCK1 antibody, PEPCKC antibody

Database links

Human UniProt/Swiss-Prot:P35558

Protein names

MGC22652, PEPCK-C, PEPCK1, PEPCKC

Protein function

Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.

Protein tissue specificity

Major sites of expression are liver, kidney and adipocytes.

Protein sequence and domain

Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

Protein post-translational modifications

Lysine acetylation by p300/EP300 is increased on high glucose conditions and promotes ubiquitination by UBR5, acetylation is enhanced in the presence of BAG6. Deacetylated by SIRT2.; Ubiquitination by UBR5 leads to proteasomal degradation.

Protein cellular localization

Cytoplasm.

Background

PCK1(Phosphoenolpyruvate carboxykinase, cytosolic) is also named as PEPCK1 and belongs to the phosphoenolpyruvate carboxykinase [GTP] family. It catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. It is also a main control point for the regulation of gluconeogenesis. In eukaryotes there are two isozymes: a cytoplasmic one and a mitochondrial one. Defects in PCK1 are the cause of cytosolic phosphoenolpyruvate carboxykinase deficiency (C-PEPCKD). This antibody is specific to PCK1.

Research area

All research areas>Signaling Intermediates>PEPCK
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize PCK1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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