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Rabbit polyclonal PDE5A antibody (A6831)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal PDE5A antibody (A6831)
Supplier: ABclonal Inc.
Recommended applications: WB
Recommended dilution:
WB 1:500 – 1:2000
Recommended protocols: check protocols
Image descriptions:
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Alternative names:
Check alternative names for the antibody
ExpandCN5A antibody, PDE5 antibody, CGB-PDE antibody
5”-cyclic phosphodiesterase antibody|CGB PDE antibody|CGB-PDE antibody|CGBPDE antibody|cGMP binding cGMP specific 3′ 5′ cyclic nucleotide phosphodiesterase antibody|cGMP binding cGMP specific 35 cyclic nucleotide phosphodiesterase antibody|cGMP binding cGMP specific phosphodiesterase antibody|cGMP binding/cGMP specific phosphodiesterase antibody|cGMP specific 3’5′ cyclic phosphodiesterase antibody|cGMP specific phosphodiesterase PDE5A2 antibody|cGMP specific phosphodiesterase type 5A antibody|cGMP-binding cGMP-specific phosphodiesterase antibody|cGMP-specific 3” antibody|CN5A antibody|CN5N antibody|PDE 5 antibody|PDE 5A antibody|PDE5 antibody|Pde5a antibody|PDE5A_HUMAN antibody|PDE5A1 antibody|Phosphodiesterase 5A antibody|Phosphodiesterase 5A cGMP specific antibody|Phosphodiesterase isozyme 5 antibody|Anti-PDE5A antibody (ab14672)
SCBT cat No: sc-398747|sc-32884|sc-30459|
Name | Rabbit polyclonal PDE5A antibody |
---|---|
Catalogue No. | A6831 |
Reactivity | Human, Mouse, Rat |
Immunogen | Recombinant protein of human PDE5A |
Host | Rabbit |
Applications | WB |
Recommended dilution | WB 1:500 – 1:2000 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Molecular weight | Predicted: 100kDa/Observed: Refer to figures |
Formulation | PDE5A antibody was tube-contained. |
Purification | PDE5A antibody was purified using affinity purification. |
Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
Alternative antibody names | CN5A antibody, PDE5 antibody, CGB-PDE antibody |
Database links | Human UniProt/Swiss-Prot:O76074 |
Protein names | CN5A, PDE5, CGB-PDE |
Protein function | Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5′-GMP . Specifically regulates nitric-oxide-generated cGMP . |
Protein tissue specificity | Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung. |
Protein sequence and domain | Composed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain which contains two homologous allosteric cGMP-binding regions, A and B.Belongs to the cyclic nucleotide phosphodiesterase family.; Contains 2 GAF domains. |
Protein post-translational modifications | Phosphorylation is regulated by binding of cGMP to the two allosteric sites (By similarity). Phosphorylation by PRKG1 leads to its activation. |
Background | This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5′-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. |
Note | AntibodyPlus can customize PDE5A antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
Product type | Primary antibody |
Supplier | ABclonal Inc. |
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