Rabbit polyclonal PDE6B antibody (A6942)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PDE6B antibody (A6942)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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rd1 antibody, PDEB antibody, RP40 antibody, CSNB3 antibody, CSNBAD2 antibody
5”-cyclic phosphodiesterase subunit beta antibody|Congenital stationary night blindness 3 autosomal dominant antibody|CSNB 3 antibody|CSNB3 antibody|CSNBAD2 antibody|GMP PDE beta antibody|GMP-PDE beta antibody|PDE 6 beta antibody|PDE 6B antibody|PDE6B antibody|PDE6B_HUMAN antibody|PDEB antibody|Phosphodiesterase 6B antibody|Phosphodiesterase 6B cGMP specific rod beta antibody|Rd 1 antibody|Rd1 antibody|Rod cGMP phosphodiesterase beta subunit antibody|Rod cGMP specific 3′ 5′ cyclic phosphodiesterase beta subunit antibody|Rod cGMP-specific 3” antibody|RP40 antibody|Anti-PDE6 beta antibody (ab5663)

SCBT cat No: sc-377486|sc-30719|

Name

Rabbit polyclonal PDE6B antibody

Catalogue No.

A6942

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PDE6B

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 98kDa/Observed: Refer to figures

Formulation

PDE6B antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PDE6B antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

rd1 antibody, PDEB antibody, RP40 antibody, CSNB3 antibody, CSNBAD2 antibody

Database links

Human UniProt/Swiss-Prot:P35913

Protein names

rd1, PDEB, RP40, CSNB3, CSNBAD2

Protein function

This protein participates in processes of transmission and amplification of the visual signal. Necessary for the formation of a functional phosphodiesterase holoenzyme.

Protein sequence and domain

Belongs to the cyclic nucleotide phosphodiesterase family.; Contains 2 GAF domains.

Protein cellular localization

Membrane; Lipid-anchor.

Background

Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize PDE6B antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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