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Rabbit Polyclonal PDF antibody (A10458)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit Polyclonal PDF antibody.
Check alternative names for the antibodyExpand
CG6496 antibody|DEFM_HUMAN antibody|mitochondrial antibody|Pdf antibody|PDF1A antibody|Peptide deformylase antibody|Peptide deformylase like protein antibody|Peptide deformylase, mitochondrial antibody|Polypeptide deformylase antibody|Anti-PDF antibody (ab76753)
SCBT cat No:
Rabbit Polyclonal PDF antibody
|Catalogue No.|| |
Recombinant protein of human PDF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
PDF antibody was tube-contained.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/Q9HBH1">Q9HBH1</a>
|Protein function|| |
Removes the formyl group from the N-terminal Met of newly synthesized proteins.
|Protein tissue specificity|| |
|Protein sequence and domain|| |
Belongs to the polypeptide deformylase family.
|Protein cellular localization|| |
Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.
AntibodyPlus can customize PDF antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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