Rabbit polyclonal PDYN antibody (A5830)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PDYN antibody (A5830)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ADCA antibody, PENKB antibody, SCA23 antibody
ADCA antibody|Beta neoendorphin dynorphin antibody|Dyn A17 antibody|leu-enkephalin antibody|leumorphin antibody|neoendorphin-dynorphin-enkephalin prepropeptide antibody|PDYN antibody|PENKB antibody|Preprodynorphin antibody|Proenkephalin B antibody|rimorphin antibody|SCA23 antibody|Anti-Dynorphin A antibody (ab11134)

SCBT cat No: sc-398808|

Name

Rabbit polyclonal PDYN antibody

Catalogue No.

A5830

Reactivity

Human

Immunogen

Recombinant protein of human PDYN

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 28kDa/Observed: Refer to figures

Formulation

PDYN antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PDYN antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ADCA antibody, PENKB antibody, SCA23 antibody

Database links

Human UniProt/Swiss-Prot:P01213

Protein names

ADCA, PENKB, SCA23

Protein function

Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity).; Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin (By similarity).; Leumorphin has a typical opiod activity and may have anti-apoptotic effect.

Protein sequence and domain

Belongs to the opioid neuropeptide precursor family.

Protein post-translational modifications

The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing.

Protein cellular localization

Secreted.

Background

The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Note

AntibodyPlus can customize PDYN antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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