Rabbit polyclonal PEX19 antibody (A5476)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal PEX19 antibody (A5476)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal PEX19 antibody.

Alternative names:

Check alternative names for the antibody

Expand

PXF antibody, HK33 antibody, PMP1 antibody, PMPI antibody, PXMP1 antibody, PBD12A antibody, D1S2223E antibody
33 kDa housekeeping protein antibody|D1S2223E antibody|HK33 antibody|Housekeeping gene 33kD antibody|OK/SW-cl.22 antibody|PBD12A antibody|Peroxin 19 antibody|Peroxin-19 antibody|Peroxisomal biogenesis factor 19 antibody|Peroxisomal farnesylated protein antibody|PEX19 antibody|PEX19_HUMAN antibody|PMP1 antibody|PMPI antibody|PXF antibody|PXMP1 antibody|Anti-PEX19 antibody [EPR9266(B)] (ab137072)

SCBT cat No: sc-136029|

Name

Rabbit polyclonal PEX19 antibody

Catalogue No.

A5476

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PEX19

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 32kDa/Observed: Refer to Figures

Formulation

PEX19 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PEX19 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PXF antibody, HK33 antibody, PMP1 antibody, PMPI antibody, PXMP1 antibody, PBD12A antibody, D1S2223E antibody

Database links

Human UniProt/Swiss-Prot:P40855

Protein names

PXF, HK33, PMP1, PMPI, PXMP1, PBD12A, D1S2223E

Protein function

Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.

Protein tissue specificity

Ubiquitously expressed. Isoform 1 is strongly predominant in all tissues except in utero where isoform 2 is the main form.

Protein sequence and domain

Belongs to the peroxin-19 family.

Protein cellular localization

Cytoplasm . Peroxisome membrane ; Lipid-anchor ; Cytoplasmic side . Note: Mainly cytoplasmic. Some fraction membrane-associated to the outer surface of peroxisomes.

Background

This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Research area

All research areas>Signaling Intermediates>Peroxin
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize PEX19 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!