Rabbit polyclonal PGF antibody (A1727)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PGF antibody (A1727)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

PGFL antibody, PLGF antibody, PlGF-2 antibody, D12S1900 antibody, SHGC-10760 antibody
D12S1900 antibody|PlGF 2 antibody|PlGF antibody|PLGF_HUMAN antibody|PlGF2 antibody|SHGC 10760 antibody|Anti-PLGF antibody (ab9542)

SCBT cat No: sc-1882|sc-101572|

Name

Rabbit polyclonal PGF antibody

Catalogue No.

A1727

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human PGF

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 24kDa/Observed: Refer to Figures

Formulation

PGF antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PGF antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PGFL antibody, PLGF antibody, PlGF-2 antibody, D12S1900 antibody, SHGC-10760 antibody

Database links

Human UniProt/Swiss-Prot:P49763

Protein names

PGFL, PLGF, PlGF-2, D12S1900, SHGC-10760

Protein function

Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.

Protein tissue specificity

While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.

Protein sequence and domain

Isoform PlGF-2 contains a basic insert which acts as a cell retention signal.Belongs to the PDGF/VEGF growth factor family.

Protein post-translational modifications

N-glycosylated.

Protein cellular localization

Secreted. Note: The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.

Background

This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize PGF antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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