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Rabbit polyclonal PHB antibody (A0056)
Supplier: ABclonal Inc.
Recommended applications: WB,IF
WB 1:500 – 1:2000 IF 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal PHB antibody.
Check alternative names for the antibodyExpand
PHB antibody,PHB1 antibody
Epididymis luminal protein 215 antibody|Epididymis secretory sperm binding protein Li 54e antibody|HEL 215 antibody|HEL S 54e antibody|PHB antibody|PHB_HUMAN antibody|PHB1 antibody|Prohibitin antibody|Anti-Prohibitin antibody [EP2803Y] (ab75766)
SCBT cat No: sc-56346|
Rabbit polyclonal PHB antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human PHB
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 30kDa/Observed: Refer to Figures
PHB antibody was tube-contained.
PHB antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
PHB antibody,PHB1 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
|Protein tissue specificity|| |
Widely expressed in different tissues.
|Protein sequence and domain|| |
Belongs to the prohibitin family.
|Protein cellular localization|| |
Mitochondrion inner membrane .
The prohibitins, called PHB1 and PHB2, are highly conserved proteins that are present in multiple compartments in eukaryotic cells. PHB1 is 30kDa tumor suppressor protein involved in cell cycle control (1). PHB1 has been found in mitochondria, the nucleus and the plasma membrane, as well as extracellularly in circulation (2). In mitochondria prohibitins mainly exist as membrane-bound ring complexes and function as chaperones maintaining mitochondrial protein stability during protein synthesis and transportation (3,4). In the nucleus prohibitins interact with transcription factors such as Rb and p53 to regulate target gene transcription (2,5). Extracellular prohibitin can bind and activate C3 to enhance complement activation (6).
AntibodyPlus can customize PHB antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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