Rabbit polyclonal PHF6 antibody (A7393)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal PHF6 antibody (A7393)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

BFLS antibody, BORJ antibody, CENP-31 antibody
AC004383.6 antibody|BFLS antibody|BORJ antibody|CENP 31 antibody|Centromere protein 31 antibody|MGC14797 antibody|OTTHUMP00000024063 antibody|PHD finger protein 6 antibody|PHD like zinc finger protein antibody|PHD-like zinc finger protein antibody|Phf6 antibody|PHF6_HUMAN antibody|Anti-PHD finger protein 6 antibody [EPR11997] (ab173304)

SCBT cat No: sc-365013|sc-514644|sc-271767|sc-365237|sc-131747|

Name

Rabbit polyclonal PHF6 antibody

Catalogue No.

A7393

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human PHF6

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 41kDa/Observed: Refer to figures

Formulation

PHF6 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

PHF6 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

BFLS antibody, BORJ antibody, CENP-31 antibody

Database links

Human UniProt/Swiss-Prot:Q8IWS0

Protein names

BFLS, BORJ, CENP-31

Protein function

Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.

Protein tissue specificity

Ubiquitously expressed.

Protein sequence and domain

The PHD-type zinc finger 1 mediates both nucleolar localization and interaction with UBTF.; The ePHD2 domain folds as an integrated structural module comprizing the C2HC pre-PHD-type 2 zinc finger and the PHD-type 2 zinc finger. It mediates non-specific binding to dsDNA, but doesn’t bind histones in contrast to many PHD-type zinc fingers.Contains 2 C2HC pre-PHD-type zinc fingers.; Contains 2 PHD-type zinc fingers.

Protein cellular localization

Nucleus. Nucleus, nucleolus. Chromosome, centromere, kinetochore . Note: Nuclear, it particularly localizes to the nucleolus.

Background

This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms.

Research area

All research areas>Transcription Regulators>PHF
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize PHF6 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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