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Rabbit Polyclonal Phospho-20S Proteasome alpha3 (S250) antibody (STJ90556)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for 20S Proteasome alpha3 (phospho Ser250) Polyclonal Antibody.
Check alternative names for the antibodyExpand
PSMA3 antibody, HC8 antibody, PSC8 antibody,|HC8 antibody|Macropain subunit C8 antibody|MGC12306 antibody|MGC32631 antibody|Multicatalytic endopeptidase complex subunit C8 antibody|Proteasome (prosome macropain) subunit alpha type 3 antibody|Proteasome alpha 3 subunit antibody|Proteasome component C8 antibody|Proteasome subunit alpha type 3 antibody|Proteasome subunit alpha type-3 antibody|Proteasome subunit C8 antibody|PSA3_HUMAN antibody|PSC8 antibody|psmA3 antibody|Anti-Proteasome 20S alpha 3 antibody [EPR5455] (ab109532)
SCBT cat No: sc-54707|sc-166205|sc-166206|sc-54670|sc-67340|
20S Proteasome alpha3 (phospho Ser250) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-20S Proteasome alpha3 (S250) Polyclonal Antibody detects endogenous levels of 20S Proteasome alpha3 protein only when phosphorylated at S250.
Synthesized phospho-peptide derived from 20S Proteasome alpha3 (phospho Ser250) at AA range 190-270
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
|Molecular weight|| |
20S Proteasome alpha3 (phospho Ser250) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
20S Proteasome alpha3 (phospho Ser250) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Proteasome subunit alpha type-3 antibody, Macropain subunit C8 antibody, Multicatalytic endopeptidase complex subunit C8 antibody, Proteasome component C8 antibody
|Protein names|| |
Proteasome subunit alpha type-3 , Macropain subunit C8 , Multicatalytic endopeptidase complex subunit C8 , Proteasome component C8
|Protein function|| |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2. / Cleavage of peptide bonds with very broad specificity.
|Protein tissue specificity|| |
Down-regulated by antioxidants BO-653 and probucol. Up-regulated by bacterial lipopolysaccharides (LPS) and TNF.
|Protein sequence and domain|| |
Belongs to the peptidase T1A family.
|Protein cellular localization|| |
Cytoplasm / Nucleus
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St John’s Laboratory Ltd.
|Product type|| |
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