Rabbit Polyclonal Phospho-4.1R (Y660) antibody (STJ90628)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-4.1R (Y660) antibody (STJ90628)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for 4.1R (phospho Tyr660) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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EPB41 antibody, E41P antibody,|4.1R antibody|41_HUMAN antibody|Band 4.1 antibody|E41P antibody|EL 1 antibody|EL1 antibody|EL1 gene antibody|Elliptocytosis 1 antibody|Elliptocytosis 1 RH linked antibody|EPB 4.1 antibody|EPB 41 antibody|EPB4.1 antibody|Epb41 antibody|Erythrocyte membrane protein band 4.1 (elliptocytosis 1 RH linked) antibody|Erythrocyte membrane protein band 4.1 antibody|Erythrocyte surface protein band 4.1 antibody|HE antibody|P4.1 antibody|Protein 4.1 antibody|Protein 4.1, red blood cell type antibody|Anti-EPB41 antibody (ab54597)
SCBT cat No: sc-398983|sc-166759|sc-514096|sc-366179|sc-25967|sc-25968|

 

Name

4.1R (phospho Tyr660) Polyclonal Antibody

Catalogue No.

STJ90628

Reactivity

Human, Mouse

Specificity

Phospho-4.1R (Y660) Polyclonal Antibody detects endogenous levels of 4.1R protein only when phosphorylated at Y660.

Immunogen

Synthesized phospho-peptide derived from 41R (phospho Tyr660) at AA range 600-680

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

60 kDa

Formulation

4.1R (phospho Tyr660) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

4.1R (phospho Tyr660) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Protein 4.1 antibody, P4.1 antibody, 4.1R antibody, Band 4.1 antibody, EPB4.1 antibody

Database links

Human UniProt/Swiss-Prot:P11171;Mouse UniPort/Swiss-Prot: P48193;Human Entrez Gene: 2035;Mouse Entrez Gene: 269587;Rat Entrez Gene: Rn.22747

Protein names

Protein 4.1 , P4.1 , 4.1R , Band 4.1 , EPB4.1

Protein function

Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes.

Involvement in disease

Elliptocytosis 1 (EL1) [MIM:611804]: A Rhesus-linked form of hereditary elliptocytosis, a genetically heterogeneous, autosomal dominant hematologic disorder. It is characterized by variable hemolytic anemia and elliptical or oval red cell shape. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Contains 1 FERM domain.

Protein post-translational modifications

Phosphorylated at multiple sites by different protein kinases and each phosphorylation event selectively modulates the protein’s functions. / Phosphorylation on Tyr-660 reduces the ability of 4.1 to promote the assembly of the spectrin/actin/4.1 ternary complex. / O-glycosylated; contains N-acetylglucosamine side chains in the C-terminal domain.

Protein cellular localization

Cytoplasm > cytoskeleton / Cytoplasm > cell cortex / Nucleus

Research area

All research areas>Signaling Intermediates>4.1R
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize 4.1R (phospho Tyr660) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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