No products in the cart.
Rabbit Polyclonal Phospho-53BP1 (S6) antibody (STJ90870)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for 53BP1 (phospho Ser6) Polyclonal Antibody.
Check alternative names for the antibodyExpand
TP53BP1 antibody,|53 BP1 antibody|53BP1 antibody|FLJ41424 antibody|MGC138366 antibody|p202 antibody|p53 binding protein 1 antibody|p53 BP1 antibody|p53-binding protein 1 antibody|p53BP1 antibody|TP53 BP1 antibody|TP53B_HUMAN antibody|Tp53bp1 antibody|TRP53 BP1 antibody|Tumor protein 53 binding protein 1 antibody|Tumor protein p53 binding protein 1 antibody|Tumor suppressor p53 binding protein 1 antibody|Tumor suppressor p53-binding protein 1 antibody|Anti-53BP1 antibody (ab36823)
SCBT cat No: sc-135749|sc-135748|
53BP1 (phospho Ser6) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat, Monkey
Phospho-53BP1 (S6) Polyclonal Antibody detects endogenous levels of 53BP1 protein only when phosphorylated at S6.
Synthesized phospho-peptide derived from 53BP1 (phospho Ser6) at AA range 1-80
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
|Molecular weight|| |
53BP1 (phospho Ser6) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
53BP1 (phospho Ser6) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Tumor suppressor p53-binding protein 1 antibody, 53BP1 antibody, p53-binding protein 1 antibody, p53BP1 antibody
|Protein names|| |
Tumor suppressor p53-binding protein 1 , 53BP1 , p53-binding protein 1 , p53BP1
|Protein function|| |
Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.
|Involvement in disease|| |
Note: A chromosomal aberration involving TP53BP1 is found in a form of myeloproliferative disorder chronic with eosinophilia. Translocation t(5;15)(q33;q22) with PDGFRB creating a TP53BP1-PDGFRB fusion protein. .
|Protein sequence and domain|| |
The Tudor-like region mediates binding to H4K20me2. / Contains 2 BRCT domains.
|Protein post-translational modifications|| |
Asymmetrically dimethylated on Arg residues by PRMT1. Methylation is required for DNA binding. / Phosphorylated at basal level in the absence of DNA damage. Hyper-phosphorylated in an ATM-dependent manner in response to DNA damage induced by ionizing radiation. Hyper-phosphorylated in an ATR-dependent manner in response to DNA damage induced by UV irradiation. Dephosphorylated by PPP5C.
|Protein cellular localization|| |
Nucleus / Chromosome > centromere > kinetochore
AntibodyPlus can customize 53BP1 (phospho Ser6) Antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: