Rabbit Polyclonal Phospho-ACCalpha (S80) antibody (STJ90780)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-ACCalpha (S80) antibody (STJ90780)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for ACCalpha (phospho Ser80) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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ACACA antibody, ACAC antibody, ACC1 antibody, ACCA antibody,|ACAC antibody|ACACA antibody|ACACA_HUMAN antibody|ACACB antibody|ACC alpha antibody|ACC antibody|ACC beta antibody|ACC-alpha antibody|ACC1 antibody|ACC2 antibody|ACCA antibody|ACCB antibody|Acetyl CoA carboxylase 1 antibody|Acetyl CoA carboxylase 2 antibody|Acetyl CoA carboxylase alpha antibody|Acetyl CoA carboxylase beta antibody|Acetyl Coenzyme A carboxylase alpha antibody|Acetyl Coenzyme A carboxylase beta antibody|Biotin carboxylase antibody|COA1 antibody|COA2 antibody|HACC275 antibody|OTTHUMP00000164069 antibody|OTTHUMP00000164070 antibody|OTTHUMP00000164076 antibody|OTTHUMP00000240532 antibody|Anti-Acetyl Coenzyme A Carboxylase antibody [EP687Y] (ab45174)
SCBT cat No: sc-26821|sc-26820|sc-377313|sc-50387|sc-377318|

 

Name

ACCalpha (phospho Ser80) Polyclonal Antibody

Catalogue No.

STJ90780

Reactivity

Human, Mouse, Rat

Specificity

Phospho-ACCalpha (S80) Polyclonal Antibody detects endogenous levels of ACCalpha protein only when phosphorylated at S80.

Immunogen

Synthesized phospho-peptide derived from ACCalpha (phospho Ser80) at AA range 20-100

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

265 kDa

Formulation

ACCalpha (phospho Ser80) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

ACCalpha (phospho Ser80) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Acetyl-CoA carboxylase 1 antibody, ACC1 antibody, ACC-alpha antibody

Database links

Human UniProt/Swiss-Prot:Q13085;Mouse UniPort/Swiss-Prot: Q5SWU9;Rat UniProt/Swiss-Port: P11497;Human Entrez Gene: 31;Mouse Entrez Gene: 107476;Rat Entrez Gene: Rn.163753

Protein names

Acetyl-CoA carboxylase 1 , ACC1 , ACC-alpha

Protein function

Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. / ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. / ATP + biotin-[carboxyl-carrier-protein] + HCO3- = ADP + phosphate + carboxy-biotin-[carboxyl-carrier-protein]. / biotin / Mn2+ / By phosphorylation (By similarity). Activity is increased by oligomerization. Citrate and MID1IP1 promote oligomerization. /

Protein tissue specificity

Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.

Involvement in disease

Acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:613933]: An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Contains 1 ATP-grasp domain. / Contains 1 biotin carboxylation domain. / Contains 1 biotinyl-binding domain. / Contains 1 carboxyltransferase domain.

Protein post-translational modifications

Phosphorylation on Ser-1263 is required for interaction with BRCA1.

Protein cellular localization

Cytoplasm

Research area

All research areas>Synthesis and Degradation>ACC
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize ACCalpha (phospho Ser80) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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