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Rabbit Polyclonal Phospho-ACCalpha (S80) antibody (STJ90780)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for ACCalpha (phospho Ser80) Polyclonal Antibody.
Check alternative names for the antibodyExpand
ACACA antibody, ACAC antibody, ACC1 antibody, ACCA antibody,|ACAC antibody|ACACA antibody|ACACA_HUMAN antibody|ACACB antibody|ACC alpha antibody|ACC antibody|ACC beta antibody|ACC-alpha antibody|ACC1 antibody|ACC2 antibody|ACCA antibody|ACCB antibody|Acetyl CoA carboxylase 1 antibody|Acetyl CoA carboxylase 2 antibody|Acetyl CoA carboxylase alpha antibody|Acetyl CoA carboxylase beta antibody|Acetyl Coenzyme A carboxylase alpha antibody|Acetyl Coenzyme A carboxylase beta antibody|Biotin carboxylase antibody|COA1 antibody|COA2 antibody|HACC275 antibody|OTTHUMP00000164069 antibody|OTTHUMP00000164070 antibody|OTTHUMP00000164076 antibody|OTTHUMP00000240532 antibody|Anti-Acetyl Coenzyme A Carboxylase antibody [EP687Y] (ab45174)
SCBT cat No: sc-26821|sc-26820|sc-377313|sc-50387|sc-377318|
ACCalpha (phospho Ser80) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-ACCalpha (S80) Polyclonal Antibody detects endogenous levels of ACCalpha protein only when phosphorylated at S80.
Synthesized phospho-peptide derived from ACCalpha (phospho Ser80) at AA range 20-100
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
|Molecular weight|| |
ACCalpha (phospho Ser80) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ACCalpha (phospho Ser80) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Acetyl-CoA carboxylase 1 antibody, ACC1 antibody, ACC-alpha antibody
|Protein names|| |
Acetyl-CoA carboxylase 1 , ACC1 , ACC-alpha
|Protein function|| |
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. / ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. / ATP + biotin-[carboxyl-carrier-protein] + HCO3- = ADP + phosphate + carboxy-biotin-[carboxyl-carrier-protein]. / biotin / Mn2+ / By phosphorylation (By similarity). Activity is increased by oligomerization. Citrate and MID1IP1 promote oligomerization. /
|Protein tissue specificity|| |
Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.
|Involvement in disease|| |
Acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:613933]: An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Contains 1 ATP-grasp domain. / Contains 1 biotin carboxylation domain. / Contains 1 biotinyl-binding domain. / Contains 1 carboxyltransferase domain.
|Protein post-translational modifications|| |
Phosphorylation on Ser-1263 is required for interaction with BRCA1.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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