Rabbit Polyclonal Phospho-AMPKbeta1 (S182) antibody (STJ90171)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-AMPKbeta1 (S182) antibody (STJ90171)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for AMPKbeta1 (phospho Ser182) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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PRKAB1 antibody, AMPK antibody,|1300015D22Rik antibody|5”-AMP-activated protein kinase subunit beta-1 antibody|AAKB1_HUMAN antibody|AMP-ACTIVATED PROTEIN KINASE, NONCATALYTIC, BETA-1 antibody|AMP-activated, noncatalytic, beta-1 antibody|AMPK antibody|AMPK beta 1 chain antibody|AMPK subunit beta-1 antibody|AMPK-BETA-1 antibody|AMPKb antibody|AU021155 antibody|E430008F22 antibody|HAMPKb antibody|MGC17785 antibody|PRKAB1 antibody|Protein kinase AMP activated non catalytic subunit beta 1 antibody|Anti-AMPK beta 1 antibody [Y367] (ab32112)
SCBT cat No: sc-19133|sc-20163|sc-19132|sc-100357|sc-100358|sc-376752|

 

Name

AMPKbeta1 (phospho Ser182) Polyclonal Antibody

Catalogue No.

STJ90171

Reactivity

Human, Mouse, Rat

Specificity

Phospho-AMPKbeta1 (S182) Polyclonal Antibody detects endogenous levels of AMPKbeta1 protein only when phosphorylated at S182.

Immunogen

Synthesized phospho-peptide derived from AMPKbeta1 (phospho Ser182) at AA range 120-200

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

38 kDa

Formulation

AMPKbeta1 (phospho Ser182) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

AMPKbeta1 (phospho Ser182) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

5′-AMP-activated protein kinase subunit beta-1 antibody, AMPK subunit beta-1 antibody, AMPKb antibody

Database links

Human UniProt/Swiss-Prot:Q9Y478;Mouse UniPort/Swiss-Prot: Q9R078;Rat UniProt/Swiss-Port: P80386;Human Entrez Gene: 5564;Mouse Entrez Gene: 19079;Rat Entrez Gene: Rn.3619

Protein names

5′-AMP-activated protein kinase subunit beta-1 , AMPK subunit beta-1 , AMPKb

Protein function

Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

Protein sequence and domain

The glycogen-binding domain may target AMPK to glycogen so that other factors like glycogen-bound debranching enzyme or protein phosphatases can directly affect AMPK activity. / Belongs to the 5′-AMP-activated protein kinase beta subunit family.

Protein post-translational modifications

Phosphorylated when associated with the catalytic subunit (PRKAA1 or PRKAA2). Phosphorylated by ULK1; leading to negatively regulate AMPK activity and suggesting the existence of a regulatory feedback loop between ULK1 and AMPK.

Research area

All research areas>Kinases and Phosphatases>AMPK
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize AMPKbeta1 (phospho Ser182) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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