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Rabbit Polyclonal Phospho-AP-1 (T91) antibody (STJ90176)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;
Recommended protocols: check protocols
Click or hover above images to see image description for AP-1 (phospho Thr91) Polyclonal Antibody.
Check alternative names for the antibodyExpand
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SCBT cat No: sc-166540|sc-376488|sc-44|sc-74543|sc-1694|sc-45|sc-162685|sc-398286|sc-393629|sc-393544|sc-167469|sc-240235|sc-374394|sc-376355|
AP-1 (phospho Thr91) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-AP-1 (T91) Polyclonal Antibody detects endogenous levels of AP-1 protein only when phosphorylated at T91.
Synthesized phospho-peptide derived from AP-1 (phospho Thr91) at AA range 30-110
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;
|Molecular weight|| |
AP-1 (phospho Thr91) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
AP-1 (phospho Thr91) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Transcription factor AP-1 antibody, Activator protein 1 antibody, AP1 antibody, Proto-oncogene c-Jun antibody, V-jun avian sarcoma virus 17 oncogene homolog antibody, p39 antibody
|Protein names|| |
Transcription factor AP-1 , Activator protein 1 , AP1 , Proto-oncogene c-Jun , V-jun avian sarcoma virus 17 oncogene homolog , p39
|Protein function|| |
Transcription factor that recognizes and binds to the enhancer heptamer motif 5′-TGA[CG]TCA-3′. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells . Binds to the USP28 promoter in colorectal cancer (CRC) cells .
|Protein sequence and domain|| |
Belongs to the bZIP family. Jun subfamily. / Contains 1 bZIP (basic-leucine zipper) domain.
|Protein post-translational modifications|| |
Ubiquitinated by the SCF(FBXW7), leading to its degradation. Ubiquitination takes place following phosphorylation, that promotes interaction with FBXW7. / Phosphorylated by CaMK4 and PRKDC; phosphorylation enhances the transcriptional activity. Phosphorylated by HIPK3. Phosphorylated by DYRK2 at Ser-243; this primes the protein for subsequent phosphorylation by GSK3B at Thr-239. Phosphorylated at Thr-239, Ser-243 and Ser-249 by GSK3B; phosphorylation reduces its ability to bind DNA. Phosphorylated by PAK2 at Thr-2, Thr-8, Thr-89, Thr-93 and Thr-286 thereby promoting JUN-mediated cell proliferation and transformation. Phosphorylated by PLK3 following hypoxia or UV irradiation, leading to increase DNA-binding activity. / Acetylated at Lys-271 by EP300.
|Protein cellular localization|| |
AntibodyPlus can customize AP-1 (phospho Thr91) Antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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