Rabbit Polyclonal Phospho-BID (S78) antibody (STJ90197)

$99.00$319.00

Reactivity: Human, Mouse
Applications: IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-BID (S78) antibody (STJ90197)

Supplier: St John’s Laboratory Ltd.

Recommended applications: IHC, ELISA

Recommended dilution: IHC 1:100-1:300; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for BID (phospho Ser78) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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BID antibody,|Apoptic death agonist antibody|Apoptotic death agonist BID antibody|BH3 interacting domain death agonist antibody|BH3 interacting domain death agonist p11 antibody|BH3 interacting domain death agonist p13 antibody|BH3 interacting domain death agonist p15 antibody|BH3-interacting domain death agonist p11 antibody|BID antibody|BID isoform ES(1b) antibody|BID isoform L(2) antibody|BID isoform Si6 antibody|BID_HUMAN antibody|Desmocollin type 4 antibody|FP497 antibody|Human BID coding sequence antibody|MGC15319 antibody|MGC42355 antibody|p11 BID antibody|p13 BID antibody|p15 BID antibody|p22 BID antibody|Anti-Bid antibody [Y8] (ab32060)
SCBT cat No: sc-56025|sc-373939|sc-6538|sc-6291|sc-514622|sc-11423|sc-6539|sc-376866|

 

Name

BID (phospho Ser78) Polyclonal Antibody

Catalogue No.

STJ90197

Reactivity

Human, Mouse

Specificity

Phospho-BID (S78) Polyclonal Antibody detects endogenous levels of BID protein only when phosphorylated at S78.

Immunogen

Synthesized phospho-peptide derived from BID (phospho Ser78) at AA range 20-100

Host

Rabbit

Applications

IHC, ELISA

Recommended dilution

IHC 1:100-1:300; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

21 kDa

Formulation

BID (phospho Ser78) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

BID (phospho Ser78) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

BH3-interacting domain death agonist antibody, p22 BID antibody, BID antibody

Database links

Human UniProt/Swiss-Prot:P55957;Mouse UniPort/Swiss-Prot: P70444;Rat UniProt/Swiss-Port: Q9JLT6;Human Entrez Gene: 637;Mouse Entrez Gene: 12122;Rat Entrez Gene: Rn.31142

Protein names

BH3-interacting domain death agonist , p22 BID , BID

Protein function

The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.

Protein tissue specificity

Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level).

Protein sequence and domain

Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.

Protein post-translational modifications

TNF-alpha induces a caspase-mediated cleavage of p22 BID into a major p15 and minor p13 and p11 products. / p15 BID is ubiquitinated by ITCH; ubiquitination results in proteasome-dependent degradation.

Protein cellular localization

Cytoplasm / Mitochondrion membrane / Mitochondrion membrane / Mitochondrion membrane / Cytoplasm / Cytoplasm / Mitochondrion membrane

Research area

All research areas>Tumor Suppressor/Apoptosis>BID
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize BID (phospho Ser78) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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