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Rabbit Polyclonal Phospho-BLM (T99) antibody (STJ91066)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for BLM (phospho Thr99) Polyclonal Antibody.
Check alternative names for the antibodyExpand
BLM antibody, RECQ2 antibody, RECQL3 antibody,|Blm antibody|BLM_HUMAN antibody|Bloom syndrome antibody|Bloom syndrome protein antibody|Bloom syndrome RecQ helicase like antibody|BS antibody|DNA helicase antibody|DNA helicase RecQ like type 2 antibody|MGC126616 antibody|MGC131618 antibody|MGC131620 antibody|RECQ 2 antibody|RECQ like antibody|RecQ like type 2 antibody|RecQ protein like 3 antibody|RecQ protein-like 3 antibody|RecQ-like type 2 antibody|RecQ2 antibody|RECQL 2 antibody|RECQL 3 antibody|RECQL2 antibody|RECQL3 antibody|type 2 antibody|Anti-Blooms Syndrome Protein Blm antibody (ab2179)
SCBT cat No: sc-70426|sc-365753|sc-13584|sc-376237|sc-7790|sc-376616|sc-14018|sc-7789|
BLM (phospho Thr99) Polyclonal Antibody
|Catalogue No.|| |
Phospho-BLM (T99) Polyclonal Antibody detects endogenous levels of BLM protein only when phosphorylated at T99.
Synthesized phospho-peptide derived from BLM (phospho Thr99) at AA range 40-120
WB, IHC, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;
|Molecular weight|| |
BLM (phospho Thr99) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
BLM (phospho Thr99) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Bloom syndrome protein antibody, DNA helicase, RecQ-like type 2 antibody, RecQ2 antibody, RecQ protein-like 3 antibody
|Protein names|| |
Bloom syndrome protein , DNA helicase, RecQ-like type 2 , RecQ2 , RecQ protein-like 3
|Protein function|| |
Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3′-5′ direction. Involved in 5′-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5′-ssDNA. Negatively regulates sister chromatid exchange (SCE). / ATP + H2O = ADP + phosphate.
|Involvement in disease|| |
Bloom syndrome (BLM) [MIM:210900]: An autosomal recessive disorder. It is characterized by proportionate pre- and postnatal growth deficiency, sun-sensitive telangiectatic hypo- and hyperpigmented skin, predisposition to malignancy, and chromosomal instability. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the helicase family. RecQ subfamily. / Contains 1 helicase ATP-binding domain. / Contains 1 helicase C-terminal domain. / Contains 1 HRDC domain.
|Protein post-translational modifications|| |
Phosphorylated in response to DNA damage. Phosphorylation requires the FANCA-FANCC-FANCE-FANCF-FANCG protein complex, as well as the presence of RMI1.
|Protein cellular localization|| |
AntibodyPlus can customize BLM (phospho Thr99) Antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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