Rabbit Polyclonal Phospho-BLM (T99) antibody (STJ91066)

$99.00$319.00

Reactivity: Human
Applications: WB, IHC, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-BLM (T99) antibody (STJ91066)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for BLM (phospho Thr99) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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BLM antibody, RECQ2 antibody, RECQL3 antibody,|Blm antibody|BLM_HUMAN antibody|Bloom syndrome antibody|Bloom syndrome protein antibody|Bloom syndrome RecQ helicase like antibody|BS antibody|DNA helicase antibody|DNA helicase RecQ like type 2 antibody|MGC126616 antibody|MGC131618 antibody|MGC131620 antibody|RECQ 2 antibody|RECQ like antibody|RecQ like type 2 antibody|RecQ protein like 3 antibody|RecQ protein-like 3 antibody|RecQ-like type 2 antibody|RecQ2 antibody|RECQL 2 antibody|RECQL 3 antibody|RECQL2 antibody|RECQL3 antibody|type 2 antibody|Anti-Blooms Syndrome Protein Blm antibody (ab2179)
SCBT cat No: sc-70426|sc-365753|sc-13584|sc-376237|sc-7790|sc-376616|sc-14018|sc-7789|

 

Name

BLM (phospho Thr99) Polyclonal Antibody

Catalogue No.

STJ91066

Reactivity

Human

Specificity

Phospho-BLM (T99) Polyclonal Antibody detects endogenous levels of BLM protein only when phosphorylated at T99.

Immunogen

Synthesized phospho-peptide derived from BLM (phospho Thr99) at AA range 40-120

Host

Rabbit

Applications

WB, IHC, IF, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

159 kDa

Formulation

BLM (phospho Thr99) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

BLM (phospho Thr99) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Bloom syndrome protein antibody, DNA helicase, RecQ-like type 2 antibody, RecQ2 antibody, RecQ protein-like 3 antibody

Database links

Human UniProt/Swiss-Prot:P54132;Mouse UniPort/Swiss-Prot: O88700;Human Entrez Gene: 641;Mouse Entrez Gene: 12144;

Protein names

Bloom syndrome protein , DNA helicase, RecQ-like type 2 , RecQ2 , RecQ protein-like 3

Protein function

Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3′-5′ direction. Involved in 5′-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5′-ssDNA. Negatively regulates sister chromatid exchange (SCE). / ATP + H2O = ADP + phosphate.

Involvement in disease

Bloom syndrome (BLM) [MIM:210900]: An autosomal recessive disorder. It is characterized by proportionate pre- and postnatal growth deficiency, sun-sensitive telangiectatic hypo- and hyperpigmented skin, predisposition to malignancy, and chromosomal instability. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the helicase family. RecQ subfamily. / Contains 1 helicase ATP-binding domain. / Contains 1 helicase C-terminal domain. / Contains 1 HRDC domain.

Protein post-translational modifications

Phosphorylated in response to DNA damage. Phosphorylation requires the FANCA-FANCC-FANCE-FANCF-FANCG protein complex, as well as the presence of RMI1.

Protein cellular localization

Nucleus

Research area

All research areas>Transcription Regulators>BLM
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize BLM (phospho Thr99) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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