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Rabbit Polyclonal Phospho-c-Myb (S12) antibody (STJ90821)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for c-Myb (phospho Ser12) Polyclonal Antibody.
Check alternative names for the antibodyExpand
MYB antibody,|C myb antibody|C myb protein antibody|Cmyb antibody|MYB antibody|Myb proto oncogene antibody|V myb myeloblastosis viral oncogene homolog antibody|Phospho anti-v-Myb + c-Myb (S11) antibody [EP769Y] – ChIP Grade (ab45150)
SCBT cat No: sc-517|sc-74512|sc-7874|sc-516|sc-70469|sc-53854|sc-40|sc-47694|
c-Myb (phospho Ser12) Polyclonal Antibody
|Catalogue No.|| |
Phospho-c-Myb (S12) Polyclonal Antibody detects endogenous levels of c-Myb protein only when phosphorylated at S12.
Synthesized phospho-peptide derived from c-Myb (phospho Ser12) at AA range 1-80
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
|Molecular weight|| |
c-Myb (phospho Ser12) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
c-Myb (phospho Ser12) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Transcriptional activator Myb antibody, Proto-oncogene c-Myb antibody
|Protein names|| |
Transcriptional activator Myb , Proto-oncogene c-Myb
|Protein function|| |
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5′-YAAC[GT]G-3′. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
|Protein tissue specificity|| |
Negatively regulated by microRNA-155 (miR-155).
|Protein sequence and domain|| |
Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression. / Contains 3 HTH myb-type DNA-binding domains.
|Protein post-translational modifications|| |
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation. / Phosphorylated by NLK on multiple sites, which induces proteasomal degradation. / Phosphorylated by HIPK1. This phosphorylation reduces MYB transcription factor activity but not MYB protein levels.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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