Rabbit Polyclonal Phospho-c-Myb (S12) antibody (STJ90821)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-c-Myb (S12) antibody (STJ90821)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for c-Myb (phospho Ser12) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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MYB antibody,|C myb antibody|C myb protein antibody|Cmyb antibody|MYB antibody|Myb proto oncogene antibody|V myb myeloblastosis viral oncogene homolog antibody|Phospho anti-v-Myb + c-Myb (S11) antibody [EP769Y] – ChIP Grade (ab45150)
SCBT cat No: sc-517|sc-74512|sc-7874|sc-516|sc-70469|sc-53854|sc-40|sc-47694|

 

Name

c-Myb (phospho Ser12) Polyclonal Antibody

Catalogue No.

STJ90821

Reactivity

Human, Mouse

Specificity

Phospho-c-Myb (S12) Polyclonal Antibody detects endogenous levels of c-Myb protein only when phosphorylated at S12.

Immunogen

Synthesized phospho-peptide derived from c-Myb (phospho Ser12) at AA range 1-80

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

65 kDa

Formulation

c-Myb (phospho Ser12) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

c-Myb (phospho Ser12) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Transcriptional activator Myb antibody, Proto-oncogene c-Myb antibody

Database links

Human UniProt/Swiss-Prot:P10242;Mouse UniPort/Swiss-Prot: P06876;Human Entrez Gene: 4602;Mouse Entrez Gene: 17863;

Protein names

Transcriptional activator Myb , Proto-oncogene c-Myb

Protein function

Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5′-YAAC[GT]G-3′. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Protein tissue specificity

Negatively regulated by microRNA-155 (miR-155).

Protein sequence and domain

Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression. / Contains 3 HTH myb-type DNA-binding domains.

Protein post-translational modifications

Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation. / Phosphorylated by NLK on multiple sites, which induces proteasomal degradation. / Phosphorylated by HIPK1. This phosphorylation reduces MYB transcription factor activity but not MYB protein levels.

Protein cellular localization

Nucleus

Research area

All research areas>Transcription Regulators>Myb
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize c-Myb (phospho Ser12) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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