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Rabbit Polyclonal Phospho-c-Rel (S503) antibody (STJ91012)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for c-Rel (phospho Ser503) Polyclonal Antibody.
Check alternative names for the antibodyExpand
REL antibody,|Avian reticuloendotheliosis antibody|C REL antibody|C Rel protein antibody|c Rel proto oncogene protein antibody|Oncogene REL antibody|Oncogene REL avian reticuloendotheliosis antibody|Proto-oncogene c-Rel antibody|REL antibody|REL_HUMAN antibody|v rel avian reticuloendotheliosis viral oncogene homolog antibody|v rel reticuloendotheliosis viral oncogene homolog antibody|V rel reticuloendotheliosis viral oncogene homolog (avian) antibody|Phospho anti-c-Rel (S503) antibody (ab30624)
SCBT cat No: sc-365694|sc-6955|sc-71|sc-373713|sc-365720|sc-70|sc-272|
c-Rel (phospho Ser503) Polyclonal Antibody
|Catalogue No.|| |
Phospho-c-Rel (S503) Polyclonal Antibody detects endogenous levels of c-Rel protein only when phosphorylated at S503.
Synthesized phospho-peptide derived from c-Rel (phospho Ser503) at AA range 440-520
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000;
|Molecular weight|| |
c-Rel (phospho Ser503) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
c-Rel (phospho Ser503) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Proto-oncogene c-Rel antibody
|Protein names|| |
|Protein function|| |
Proto-oncogene that may play a role in differentiation and lymphopoiesis. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. The NF-kappa-B heterodimer RELA/p65-c-Rel is a transcriptional activator.
|Protein sequence and domain|| |
Contains 1 RHD (Rel-like) domain.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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