Rabbit Polyclonal Phospho-C3G (Y504) antibody (STJ90537)

$99.00$319.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-C3G (Y504) antibody (STJ90537)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for C3G (phospho Tyr504) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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RAPGEF1 antibody, GRF2 antibody,|C3G antibody|C3G protein antibody|CRK SH3 binding GNRP antibody|CRK SH3-binding GNRP antibody|DKFZp781P1719 antibody|GRF 2 antibody|GRF2 antibody|Guanine nucleotide releasing factor 2 (specific for crk proto oncogene) antibody|Guanine nucleotide releasing factor 2 antibody|Guanine nucleotide-releasing factor 2 antibody|OTTHUMP00000064558 antibody|Protein C3G antibody|Rap guanine nucleotide exchange factor (GEF) 1 antibody|Rap guanine nucleotide exchange factor 1 antibody|RAPGEF 1 antibody|RAPGEF1 antibody|RPGF1_HUMAN antibody|Anti-GRF2 antibody (ab169279)
SCBT cat No: sc-869|sc-376992|sc-17840|sc-393836|sc-15359|sc-376579|

 

Name

C3G (phospho Tyr504) Polyclonal Antibody

Catalogue No.

STJ90537

Reactivity

Human

Specificity

Phospho-C3G (Y504) Polyclonal Antibody detects endogenous levels of C3G protein only when phosphorylated at Y504.

Immunogen

Synthesized phospho-peptide derived from C3G (phospho Tyr504) at AA range 440-520

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

120 kDa

Formulation

C3G (phospho Tyr504) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

C3G (phospho Tyr504) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Rap guanine nucleotide exchange factor 1 antibody, CRK SH3-binding GNRP antibody, Guanine nucleotide-releasing factor 2 antibody, Protein C3G antibody

Database links

Human UniProt/Swiss-Prot:Q13905;Human Entrez Gene: 2889;Mouse Entrez Gene: 107746;Rat Entrez Gene: Rn.85879

Protein names

Rap guanine nucleotide exchange factor 1 , CRK SH3-binding GNRP , Guanine nucleotide-releasing factor 2 , Protein C3G

Protein function

Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.

Protein tissue specificity

Ubiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver.

Protein sequence and domain

Contains 1 N-terminal Ras-GEF domain. / Contains 1 Ras-GEF domain.

Protein post-translational modifications

Phosphorylation at Tyr-504 enhances activity as Rap guanine nucleotide exchange factor.

Protein cellular localization

Early endosome

Research area

All research areas>GDP/GTP Binding Proteins>C3G
(View all antibody categories related to GDP/GTP Binding Proteins)

Note

AntibodyPlus can customize C3G (phospho Tyr504) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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