Rabbit Polyclonal Phospho-Calnexin (S583) antibody (STJ90201)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-Calnexin (S583) antibody (STJ90201)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Calnexin (phospho Ser583) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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CANX antibody,|Calnexin antibody|CALX_HUMAN antibody|CANX antibody|CNX antibody|FLJ26570 antibody|Histocompatibility complex class I antigen binding protein p88 antibody|IP90 antibody|Major histocompatibility complex class I antigen-binding protein p88 antibody|p90 antibody|Anti-Calnexin antibody (ab22595)
SCBT cat No: sc-130059|sc-70481|sc-23954|sc-6465|sc-46669|sc-11397|sc-80645|

 

Name

Calnexin (phospho Ser583) Polyclonal Antibody

Catalogue No.

STJ90201

Reactivity

Human, Mouse, Rat

Specificity

Phospho-Calnexin (S583) Polyclonal Antibody detects endogenous levels of Calnexin protein only when phosphorylated at S583.

Immunogen

Synthesized phospho-peptide derived from Calnexin (phospho Ser583) at AA range 520-600

Host

Rabbit

Applications

WB, IHC, IF, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

90 kDa

Formulation

Calnexin (phospho Ser583) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Calnexin (phospho Ser583) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Calnexin antibody, IP90 antibody, Major histocompatibility complex class I antigen-binding protein p88 antibody, p90 antibody

Database links

Human UniProt/Swiss-Prot:P27824;Mouse UniPort/Swiss-Prot: P35564;Rat UniProt/Swiss-Port: P35565;Human Entrez Gene: 821;Mouse Entrez Gene: 12330;Rat Entrez Gene: Rn.1762

Protein names

Calnexin , IP90 , Major histocompatibility complex class I antigen-binding protein p88 , p90

Protein function

Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.

Protein sequence and domain

Belongs to the calreticulin family.

Protein post-translational modifications

Phosphorylated at Ser-564 by MAPK3/ERK1. phosphorylation by MAPK3/ERK1 increases its association with ribosomes (By similarity). / Palmitoylation by DHHC6 leads to the preferential localization to the perinuclear rough ER. It mediates the association of calnexin with the ribosome-translocon complex (RTC) which is required for efficient folding of glycosylated proteins. / Ubiquitinated, leading to proteasomal degradation. Probably ubiquitinated by ZNRF4.

Protein cellular localization

Endoplasmic reticulum membrane / Single-pass type I membrane protein / Endoplasmic reticulum / Melanosome

Research area

All research areas>Transport and Trafficking>Calnexin
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus can customize Calnexin (phospho Ser583) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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