No products in the cart.
Rabbit Polyclonal Phospho-Caspase-1 (S376) antibody (STJ90909)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;
Recommended protocols: check protocols
Click or hover above images to see image description for Caspase-1 (phospho Ser376) Polyclonal Antibody.
Check alternative names for the antibodyExpand
CASP1 antibody, IL1BC antibody, IL1BCE antibody,|CASP-1 antibody|CASP1 antibody|CASP1_HUMAN antibody|Caspase 1 antibody|Caspase-1 subunit p10 antibody|ICE antibody|IL-1 beta-converting enzyme antibody|IL-1BC antibody|IL1 beta converting enzyme antibody|IL1B convertase antibody|Interleukin 1 beta convertase antibody|Interleukin 1B converting enzyme antibody|Interleukin-1 beta convertase antibody|Interleukin-1 beta-converting enzyme antibody|p45 antibody|Anti-Caspase-1 antibody
SCBT cat No: sc-514|sc-1780|sc-398715|sc-1597|sc-1218|sc-134299|
Caspase-1 (phospho Ser376) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-Caspase-1 (S376) Polyclonal Antibody detects endogenous levels of Caspase-1 protein only when phosphorylated at S376.
Synthesized phospho-peptide derived from Caspase-1 (phospho Ser376) at AA range 320-400
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;
|Molecular weight|| |
Caspase-1 (phospho Ser376) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Caspase-1 (phospho Ser376) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Caspase-1 antibody, CASP-1 antibody, Interleukin-1 beta convertase antibody, IL-1BC antibody, Interleukin-1 beta-converting enzyme antibody, ICE antibody, IL-1 beta-converting enzyme antibody, p45 antibody
|Protein names|| |
Caspase-1 , CASP-1 , Interleukin-1 beta convertase , IL-1BC , Interleukin-1 beta-converting enzyme , ICE , IL-1 beta-converting enzyme , p45
|Protein function|| |
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. / Strict requirement for an Asp residue at position P1 and has a preferred cleavage sequence of Tyr-Val-Ala-Asp-, -. / Specifically inhibited by the cowpox virus Crma protein.
|Protein tissue specificity|| |
Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.
|Protein sequence and domain|| |
Belongs to the peptidase C14A family. / Contains 1 CARD domain.
|Protein post-translational modifications|| |
The two subunits are derived from the precursor sequence by an autocatalytic mechanism.
|Protein cellular localization|| |
AntibodyPlus can customize Caspase-1 (phospho Ser376) Antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: