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Rabbit Polyclonal Phospho-CD318 (Y707) antibody (STJ90212)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for CD318 (phospho Tyr707) Polyclonal Antibody.
Check alternative names for the antibodyExpand
CDCP1 antibody, TRASK antibody, UNQ2486/PRO5773 antibody,|9030022E12Rik antibody|AA409659 antibody|CD 318 antibody|CD_antigen=CD318 antibody|CD318 antibody|CD318 antigen antibody|CDCP 1 antibody|Cdcp1 antibody|CDCP1_HUMAN antibody|CUB domain containing protein 1 antibody|CUB domain-containing protein 1 antibody|E030027H19Rik antibody|FLJ13772 antibody|FLJ22375 antibody|FLJ22969 antibody|Membrane glycoprotein gp140 antibody|MGC31813 antibody|OTTHUMP00000164120 antibody|OTTHUMP00000209568 antibody|RGD1305578 antibody|SIMA 135 antibody|SIMA135 antibody|Subtractive immunization M plus HEp3 associated 135 kDa protein antibody|Subtractive immunization M plus HEp3-associated 135 kDa protein antibody|Transmembrane and associated with src kinases antibody|TRASK antibody|Anti-CDCP1 antibody (ab1377)
SCBT cat No: sc-515545|sc-32844|sc-292398|
CD318 (phospho Tyr707) Polyclonal Antibody
|Catalogue No.|| |
Phospho-CD318 (Y707) Polyclonal Antibody detects endogenous levels of CD318 protein only when phosphorylated at Y707.
Synthesized phospho-peptide derived from human CD318 around the phosphorylation site of Y707
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000;
|Molecular weight|| |
CD318 (phospho Tyr707) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
CD318 (phospho Tyr707) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
CUB domain-containing protein 1 antibody, Membrane glycoprotein gp140 antibody, Subtractive immunization M plus HEp3-associated 135 kDa protein antibody, SIMA135 antibody, Transmembrane and associated with src kinases antibody, CD antigen CD318 antibody
|Protein names|| |
CUB domain-containing protein 1 , Membrane glycoprotein gp140 , Subtractive immunization M plus HEp3-associated 135 kDa protein , SIMA135 , Transmembrane and associated with src kinases , CD antigen CD318
|Protein function|| |
May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
|Protein tissue specificity|| |
Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells.
|Protein sequence and domain|| |
Contains 1 CUB domain.
|Protein post-translational modifications|| |
Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin analog. Tyrosine phosphorylated in response to dissociation of integrin alpha-6 beta-4 from laminin-5. / N-glycosylated. / A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). Another peptide of 80 kDa (p80) is present in cultured keratinocytes probably due to tryptic cleavage at an unidentified site on its N-terminal side. Converted to p80 by plasmin, a trypsin-like protease.
|Protein cellular localization|| |
Cell membrane / Secreted
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St John’s Laboratory Ltd.
|Product type|| |
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