Rabbit Polyclonal Phospho-CD318 (Y707) antibody (STJ90212)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-CD318 (Y707) antibody (STJ90212)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CDCP1 antibody, TRASK antibody, UNQ2486/PRO5773 antibody,|9030022E12Rik antibody|AA409659 antibody|CD 318 antibody|CD_antigen=CD318 antibody|CD318 antibody|CD318 antigen antibody|CDCP 1 antibody|Cdcp1 antibody|CDCP1_HUMAN antibody|CUB domain containing protein 1 antibody|CUB domain-containing protein 1 antibody|E030027H19Rik antibody|FLJ13772 antibody|FLJ22375 antibody|FLJ22969 antibody|Membrane glycoprotein gp140 antibody|MGC31813 antibody|OTTHUMP00000164120 antibody|OTTHUMP00000209568 antibody|RGD1305578 antibody|SIMA 135 antibody|SIMA135 antibody|Subtractive immunization M plus HEp3 associated 135 kDa protein antibody|Subtractive immunization M plus HEp3-associated 135 kDa protein antibody|Transmembrane and associated with src kinases antibody|TRASK antibody|Anti-CDCP1 antibody (ab1377)
SCBT cat No: sc-515545|sc-32844|sc-292398|

 

Name

CD318 (phospho Tyr707) Polyclonal Antibody

Catalogue No.

STJ90212

Reactivity

Human, Mouse

Specificity

Phospho-CD318 (Y707) Polyclonal Antibody detects endogenous levels of CD318 protein only when phosphorylated at Y707.

Immunogen

Synthesized phospho-peptide derived from human CD318 around the phosphorylation site of Y707

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

140,80 kDa

Formulation

CD318 (phospho Tyr707) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

CD318 (phospho Tyr707) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

CUB domain-containing protein 1 antibody, Membrane glycoprotein gp140 antibody, Subtractive immunization M plus HEp3-associated 135 kDa protein antibody, SIMA135 antibody, Transmembrane and associated with src kinases antibody, CD antigen CD318 antibody

Database links

Human UniProt/Swiss-Prot:Q9H5V8;Mouse UniPort/Swiss-Prot: Q5U462;Rat UniProt/Swiss-Port: D3ZVA1;Human Entrez Gene: 64866;Mouse Entrez Gene: 109332;Rat Entrez Gene: Rn.7729

Protein names

CUB domain-containing protein 1 , Membrane glycoprotein gp140 , Subtractive immunization M plus HEp3-associated 135 kDa protein , SIMA135 , Transmembrane and associated with src kinases , CD antigen CD318

Protein function

May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.

Protein tissue specificity

Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells.

Protein sequence and domain

Contains 1 CUB domain.

Protein post-translational modifications

Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin analog. Tyrosine phosphorylated in response to dissociation of integrin alpha-6 beta-4 from laminin-5. / N-glycosylated. / A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). Another peptide of 80 kDa (p80) is present in cultured keratinocytes probably due to tryptic cleavage at an unidentified site on its N-terminal side. Converted to p80 by plasmin, a trypsin-like protease.

Protein cellular localization

Cell membrane / Secreted

Note

AntibodyPlus can customize CD318 (phospho Tyr707) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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