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Rabbit Polyclonal Phospho-CD44 (S706) antibody (STJ90509)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:20000;
Recommended protocols: check protocols
Click or hover above images to see image description for CD44 (phospho Ser706) Polyclonal Antibody.
Check alternative names for the antibodyExpand
CD44 antibody, LHR antibody, MDU2 antibody, MDU3 antibody, MIC4 antibody,|LHR antibody|BA-1 antibody|CD 44 antibody|CD44 antibody|CD44 antigen antibody|CD44 molecule (Indian blood group) antibody|CD44 molecule antibody|CD44_HUMAN antibody|CDw44 antibody|Cell surface glycoprotein CD44 antibody|chondroitin sulfate proteoglycan 8 antibody|CSPG8 antibody|ECMR-III antibody|Epican antibody|Extracellular matrix receptor III antibody|GP90 lymphocyte homing/adhesion receptor antibody|HCELL antibody|hematopoietic cell E- and L-selectin ligand antibody|Heparan sulfate proteoglycan antibody|Hermes antigen antibody|homing function and Indian blood group system antibody|HSA antibody|HUTCH-I antibody|HUTCH1 antibody|Hyaluronate receptor antibody|IN antibody|MC56 antibody|MDU2 antibody|MDU3 antibody|MGC10468 antibody|MIC4 antibody|MUTCH1 antibody|PGP-1 antibody|PGP-I antibody|PGP1 antibody|Phagocytic glycoprotein 1 antibody|Phagocytic glycoprotein I antibody|Soluble CD44 antibody|Anti-CD44 antibody (ab157107)
SCBT cat No: sc-52536|
CD44 (phospho Ser706) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-CD44 (S706) Polyclonal Antibody detects endogenous levels of CD44 protein only when phosphorylated at S706.
Synthesized phospho-peptide derived from CD44 (phospho Ser706) at AA range 650-730
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:20000;
|Molecular weight|| |
CD44 (phospho Ser706) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
CD44 (phospho Ser706) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
CD44 antigen antibody, CDw44 antibody, Epican antibody, Extracellular matrix receptor III antibody, ECMR-III antibody, GP90 lymphocyte homing/adhesion receptor antibody, HUTCH-I antibody, Heparan sulfate proteoglycan antibody, Hermes antigen antibody, Hyaluronate receptor antibody, Phagocytic glycoprotein 1 antibody, PGP-1 antibody, Phagocytic glycoprotein I antibody, PGP-I antibody, CD antigen CD44 antibody
|Protein names|| |
CD44 antigen , CDw44 , Epican , Extracellular matrix receptor III , ECMR-III , GP90 lymphocyte homing/adhesion receptor , HUTCH-I , Heparan sulfate proteoglycan , Hermes antigen , Hyaluronate receptor , Phagocytic glycoprotein 1 , PGP-1 , Phagocytic glycoprotein I , PGP-I , CD antigen CD44
|Protein function|| |
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).
|Protein tissue specificity|| |
Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
|Protein sequence and domain|| |
The lectin-like LINK domain is responsible for hyaluronan binding. / Contains 1 Link domain.
|Protein post-translational modifications|| |
Proteolytically cleaved in the extracellular matrix by specific proteinases (possibly MMPs) in several cell lines and tumors. / N- and O-glycosylated. O-glycosylation contains more-or-less-sulfated chondroitin sulfate glycans, whose number may affect the accessibility of specific proteinases to their cleavage site(s). It is uncertain if O-glycosylation occurs on Thr-637 or Thr-638. / Phosphorylated; activation of PKC results in the dephosphorylation of Ser-706 (constitutive phosphorylation site), and the phosphorylation of Ser-672.
|Protein cellular localization|| |
Cell membrane / Single-pass type I membrane protein
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St John’s Laboratory Ltd.
|Product type|| |
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