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Rabbit Polyclonal Phospho-Cofilin (S3) antibody (STJ90230)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for Cofilin (phospho Ser3) Polyclonal Antibody.
Check alternative names for the antibodyExpand
CFL1 antibody, CFL antibody,|18 kDa phosphoprotein antibody|CFL antibody|Cofilin 1 (non-muscle) antibody|cofilin 1 antibody|Cofilin 2 (muscle) antibody|cofilin 2 antibody|Cofilin, muscle isoform antibody|Cofilin, non-muscle isoform antibody|NEM7 antibody|p18 antibody|Anti-Cofilin antibody (ab42824)
SCBT cat No: sc-53934|sc-32158|sc-32157|sc-166958|sc-32160|sc-376476|sc-33779|sc-8441|sc-136179|sc-164079|sc-130444|
Cofilin (phospho Ser3) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-Cofilin (S3) Polyclonal Antibody detects endogenous levels of Cofilin protein only when phosphorylated at S3.
Synthesized phospho-peptide derived from Cofilin (phospho Ser3) at AA range 10-90
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
|Molecular weight|| |
Cofilin (phospho Ser3) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Cofilin (phospho Ser3) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Cofilin-1 antibody, 18 kDa phosphoprotein antibody, p18 antibody, Cofilin, non-muscle isoform antibody
|Protein names|| |
Cofilin-1 , 18 kDa phosphoprotein , p18 , Cofilin, non-muscle isoform
|Protein function|| |
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation.
|Protein tissue specificity|| |
Widely distributed in various tissues.
|Protein sequence and domain|| |
Belongs to the actin-binding proteins ADF family. / Contains 1 ADF-H domain.
|Protein post-translational modifications|| |
Inactivated by phosphorylation on Ser-3. Phosphorylated on Ser-3 in resting cells (By similarity). Dephosphorylated by PDXP/chronophin; this restores its activity in promoting actin filament depolymerization. The phosphorylation of Ser-24 may prevent recognition of the nuclear localization signal (By similarity). Phosphorylated via a ARRB1-RAC1-LIMK1-PAK1 cascade upon active ligand stimulation of atypical chemokine receptor ACKR2.
|Protein cellular localization|| |
Nucleus matrix / Cytoplasm > cytoskeleton / Cell projection > ruffle membrane / Peripheral membrane protein / Cytoplasmic side / Cell projection > lamellipodium membrane / Peripheral membrane protein / Cytoplasmic side
AntibodyPlus can customize Cofilin (phospho Ser3) Antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
Displaying 1 - 1 of 1
Antibody customer reviews & validation data - 193
Validation data ID: 193
Submission date: 2017-05-21
we used this antibody to detect p-cofilin in HEK293T cells and could detect a band around 18-19 KD.
Product catalog No.
St John's Laboratory
Antibody specificity rating
Antibody overall rating
It is a good antibody for western blotting
There is no extra validation for this product yet.
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