Rabbit Polyclonal Phospho-CRMP-2 (S522) antibody (STJ90673)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Phospho-CRMP-2 (S522) antibody (STJ90673)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for CRMP-2 (phospho Ser522) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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DPYSL2 antibody, CRMP2 antibody, ULIP2 antibody,|Collapsin response mediator protein 2 antibody|DPYL 2 antibody|DPYL2 antibody|DPYL2_HUMAN antibody|DPYSL 2 antibody|Dpysl2 antibody|DRP-2 antibody|DRP2 antibody|Musunc 33 antibody|Musunc33 antibody|N2A3 antibody|TOAD 64 antibody|TOAD64 antibody|ULIP 2 protein antibody|ULIP-2 antibody|Ulip2 antibody|Unc-33-like phosphoprotein 2 antibody|Anti-CRMP2 antibody [EPR7792] (ab129082)
SCBT cat No: sc-377155|sc-30228|sc-46872|sc-365348|sc-101348|sc-25895|

 

Name

CRMP-2 (phospho Ser522) Polyclonal Antibody

Catalogue No.

STJ90673

Reactivity

Human, Mouse, Rat

Specificity

Phospho-CRMP-2 (S522) Polyclonal Antibody detects endogenous levels of CRMP-2 protein only when phosphorylated at S522.

Immunogen

Synthesized phospho-peptide derived from CRMP-2 (phospho Ser522) at AA range 460-540

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

62 kDa

Formulation

CRMP-2 (phospho Ser522) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

CRMP-2 (phospho Ser522) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Dihydropyrimidinase-related protein 2 antibody, DRP-2 antibody, Collapsin response mediator protein 2 antibody, CRMP-2 antibody, N2A3 antibody, Unc-33-like phosphoprotein 2 antibody, ULIP-2 antibody

Database links

Human UniProt/Swiss-Prot:Q16555;Mouse UniPort/Swiss-Prot: O08553;Rat UniProt/Swiss-Port: P47942;Human Entrez Gene: 1808;Mouse Entrez Gene: 12934;Rat Entrez Gene: Rn.2889

Protein names

Dihydropyrimidinase-related protein 2 , DRP-2 , Collapsin response mediator protein 2 , CRMP-2 , N2A3 , Unc-33-like phosphoprotein 2 , ULIP-2

Protein function

Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.

Protein tissue specificity

Ubiquitous.

Protein sequence and domain

Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.

Protein post-translational modifications

3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509. / Phosphorylation at Thr-514 by GSK3B abolishes tubulin-binding leading to destabilization of microtubule assembly in axons and neurodegeneration (By similarity). Phosphorylation by DYRK2 at Ser-522 is required for subsequent phosphorylation by GSK3B.

Protein cellular localization

Cytoplasm > cytosol / Cytoplasm > cytoskeleton / Membrane

Research area

All research areas>Neurobiology>CRMP
(View all antibody categories related to Neurobiology)

Note

AntibodyPlus can customize CRMP-2 (phospho Ser522) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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