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Rabbit Polyclonal Phospho-CRMP-2 (S522) antibody (STJ90673)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for CRMP-2 (phospho Ser522) Polyclonal Antibody.
Check alternative names for the antibodyExpand
DPYSL2 antibody, CRMP2 antibody, ULIP2 antibody,|Collapsin response mediator protein 2 antibody|DPYL 2 antibody|DPYL2 antibody|DPYL2_HUMAN antibody|DPYSL 2 antibody|Dpysl2 antibody|DRP-2 antibody|DRP2 antibody|Musunc 33 antibody|Musunc33 antibody|N2A3 antibody|TOAD 64 antibody|TOAD64 antibody|ULIP 2 protein antibody|ULIP-2 antibody|Ulip2 antibody|Unc-33-like phosphoprotein 2 antibody|Anti-CRMP2 antibody [EPR7792] (ab129082)
SCBT cat No: sc-377155|sc-30228|sc-46872|sc-365348|sc-101348|sc-25895|
CRMP-2 (phospho Ser522) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Phospho-CRMP-2 (S522) Polyclonal Antibody detects endogenous levels of CRMP-2 protein only when phosphorylated at S522.
Synthesized phospho-peptide derived from CRMP-2 (phospho Ser522) at AA range 460-540
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000;
|Molecular weight|| |
CRMP-2 (phospho Ser522) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
CRMP-2 (phospho Ser522) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Dihydropyrimidinase-related protein 2 antibody, DRP-2 antibody, Collapsin response mediator protein 2 antibody, CRMP-2 antibody, N2A3 antibody, Unc-33-like phosphoprotein 2 antibody, ULIP-2 antibody
|Protein names|| |
Dihydropyrimidinase-related protein 2 , DRP-2 , Collapsin response mediator protein 2 , CRMP-2 , N2A3 , Unc-33-like phosphoprotein 2 , ULIP-2
|Protein function|| |
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
|Protein tissue specificity|| |
|Protein sequence and domain|| |
Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
|Protein post-translational modifications|| |
3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509. / Phosphorylation at Thr-514 by GSK3B abolishes tubulin-binding leading to destabilization of microtubule assembly in axons and neurodegeneration (By similarity). Phosphorylation by DYRK2 at Ser-522 is required for subsequent phosphorylation by GSK3B.
|Protein cellular localization|| |
Cytoplasm > cytosol / Cytoplasm > cytoskeleton / Membrane
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St John’s Laboratory Ltd.
|Product type|| |
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